Something I found on Wiki:
Maybe there is hope of bone structure slightly changing?
http://en.wikipedia.org/wiki/Hormone_replacement_therapy_(female-to-male)BoneBoth estrogens and androgens are necessary in both biological males and females for healthy bone. (Young healthy women produce about 10 mg of testosterone monthly. Higher bone mineral density in males is associated with higher serum estrogen.)
Bone is not static. It is constantly being reabsorbed and created. Osteoporosis results when bone formation occurs at a rate less than bone resorption.
Estrogen is the predominant sex hormone that slows bone loss (even in men.)
Both estrogen and testosterone help stimulate bone formation (T, especially at puberty.)
Testosterone may cause an increase in cortical bone thickness in transgender men (however this does not necessarily translate to a greater mechanical stability.)
Transgender men who have been oophorectomized must continue androgen therapy to avoid premature osteoporosis. Estrogen supplementation is theoretically not usually necessary, as some of the injected testosterone will be aromatized into estrogen sufficient to maintain bone (as it does in biological men.) However, a single small study of trans men after oophorectomy demonstrated that androgens alone may be insufficient to retard bone loss. (van Kesteren P, et al. "Long-term follow-up of bone mineral density and bone metabolism in transsexuals treated with cross-sex hormones." Clin Endocrin. 48(3):347-54. 1998.) It is likely the case that pre-oophorectomy, residual estrogen production is protective. However, after oophorectomy, some trans men may have insufficient estrogen to retard bone loss.
Some physicians advocate a Dexa (bone density) scan at the time of oophorectomy and every year or two thereafter to diagnose osteoporosis before it becomes severe enough to be symptomatic. This is important because treatment of osteoporosis is most effective if done early.
Daily calcium supplementation and possibly Vitamin D is probably a good idea for most transgender men, but it is even more important after removal of the ovaries.
