How about something like....
A couple, man and mtf partner, travel to meet the man's parents/family for the first time. Maybe they're from the city and they have to travel to the county or something like that. They try all week to hide her transition status b/c they don't think the fam will be accepting. Hiding her transition involves a series of comedic fiasco's that get more and more outrageous until, finally, the truth comes out. Of course, everyone knew all along and is totally accepting.