The fashion business is a lot like show business - in both of them the word 'business' comes second, but the reality is that if the 'business' does not come first you never get to do the fashion or put on the show. So either find a business partner who knows business like you know fashion, or, make sure you're taking classes in marketing, business law, and bookkeeping as well as the fashion stuff.
I think they also have a lot in common in that from the outside they look all 'glamorous' but the inner reality is, as a friend of mine says a lot, 'all jackals and divas'. For starters it's probably the most exploitive industry in the world - at its base, and in its heart, it's sweatshops and child labor (and pretty much as been since the Industrial Revolution). Second, it's so cut-throat that it would shame pirates.
Clothing is one of the areas that has been the most successful (if you want to use that word) at keeping the bricks and mortar stores. People really want to try it on, see the quality, touch the fabric and all that.