Male Mice Created Without Y Chromosome

[Natasha]

Male Mice Created Without Y Chromosome

http://ts-si.org/genetics-&-genome/28187-male-mice-created-without-y-chromosome
12/26/10

Scientists have activated an ancient brain gene to create male mice without a Y chromosome, a major step toward fuller understanding of overall human sexual development. Given the provably direct similarities and predictive qualities of the mouse model organism, and the existence of masculine XX humans, the findings provide a near-definitive reset of the Y chromosome's role in human sexual development.

Males usually have one Y chromosome and one X chromosome, while females have two X chromosomes. A single gene on the Y, called SRY, triggers testes development in the early embryo, and once these begin to form, the rest of the embryo also becomes male.

However, an international collaborative team at the University of Adelaide discovered a way of creating a male mouse without a Y chromosome by activating a single gene, called SOX3, in the developing fetus. They also showed for the first time that changes in the human version of the same gene are present in some patients with disorders of sexual development.

[VanOcc]

Seriously, gender and bodies are far more complex than simply, woman are XX and men are XY. Not to mention the difference between gender and biological sex.

[spacial]

This is interesting in that these people have managed to artificially activate a gene, causing physical development which would not, normally have happened.

On  the basis of the information supplied, it sadly, doesn't explain anything at all.