It will depend on you and the lesbians. There are no rules here.
Like any other group there are positives and negatives. I personally have always been made very welcome, but I do know of transwomen who have been literally thrown out - and in fact in one case I was one of the lesbians doing the throwing.

(although actually for the record I'm technically bisexual

)
No doubt she felt it was all because she was trans, but the reality was that it was because she was a pretentious and disruptive little tit who didn't fit in!
There are also some lesbians who feel threatened by transwomen. Best thing is to understand that you can't like or understand everyone in life, so just give them their space and insist that they give you yours.