- Welcome to Susan's Place Transgender Resources.
Quote from: Jessica_K on May 21, 2024, 02:45:52 PMThe main part of the referb, however is I lovely hand built solid plinth that I acquired via a part exchange of an amp I was selling. The plinth is bare wood made of about 30 layers of high quality plywood.
I could have got it veneered, but left it naked with many layers of yacht varnish. It's now drying. I am hoping it will be dry enough to be able to rebuild it so to take the finished turntable to a group of friends on Sunday.
Quote from: Jessica_K on Yesterday at 03:57:55 PMSpot what's missing?
Quote from: LoriDee on Yesterday at 03:35:23 PMVery often, providers like to quote the Women's Health Initiative study as their guidelines. Even the FDA has warnings for Prometrium (bioidentical progesterone). I point out that the WHI study was a good thing and we learned much about Premarin (Conjugated HORSE estrogen) and synthetic progestins. The study was canceled due to too many instances of cancer in the study subjects.
I have read the study myself and there are problems with it. The purpose of the study was to determine if adding progestin to Premarin would improve the cardiovascular health of post-menopausal women. The problems with that study are:
1. Not a single participant was transgender.
2. Our prescribing protocol now includes bioidentical progesterone, not synthetic progestin. We are not prescribed CEE (Conjugated Equine Estrogen), i.e. Premarin.
3. You cannot look at the results of one drug and automatically assume that applies to all drugs in that category.
As part of that study, they looked at just Premarin and found it causes an increased risk of blood clots and stroke. They looked at just the progestins and found that it increases the risk of certain cancers. But they ignore the fact that neither of these products is found in the human body.
Yes, they are still prescribed. But as you pointed out, they do it at a low dose to avoid those risks. And some patients have a good outcome.
As yet, not one provider has been able to explain to me why we don't follow basic biology and do what the human body normally does. Estrogen levels rise at the beginning of the monthly cycle for the first half, then drop in the second half. Progesterone rises in the second half and drops at the end.
Estrogen provides fat distribution (bust, hips. and butt) and develops the ductwork inside the breast connecting to the nipple. This causes an increase in bust projection. Progesterone builds the glands (alveoli) that will produce milk later. This causes an increase in breast volume.
When pregnancy occurs, both estrogen and progesterone climb several times higher than baseline. This kicks breast development into high gear so that they will be fully matured and ready for lactation in nine months. Progesterone blocks prolactin so that lactation does not occur. Post-partum, (after birth), both hormones drop to baseline levels, allowing prolactin to cause milk ejection.
Because all of these hormones are bioidentical, because they come from the human body, the high levels do their job and do not cause all of the dangerous side-effects. If the risk is there, there would be very high numbers of pregnant women with cancer, blood clots, and stroke. But there isn't.
Sorry for the long post, but this is the long discussion I will have with my gynecologist. We will see what her response is.
Quote from: RandomStrangerX on Yesterday at 07:55:47 AM@Sarah B, @LoriDee, @SoupSarah
Thank you so much for your answers, as for I knew that I'm not alone in those feelings, but seeing it written by someone else is really, really helpful.
@Sarah B - regarding my nickname, I must admit that I didn't look up other users nicks here and just went in with something not exactly showing my desired name, etc. If you can direct me to how can I change it without creating another account, that may be helpful
Quote from: LoriDee on Yesterday at 01:26:44 PMI have been on progesterone for just over a year now. Both medicines work the same way, but bioidentical progesterone has less health risks. Synthetic progestins have been shown to increase the risk of cancers, etc. Bioidentical progesterone has no such risk. When women become pregnant both their estrogen and progesterone levels rise to high levels. Extremely few pregnant women develop cancer, therefore bioidentical is the way to go.
I still argue with my doctors who want to keep levels low "to a safe level". They ignore the biological fact that high estrogen and high progesterone are what prepare the breasts for breastfeeding. We could get to Tanner Stage 5 in 9 months! But they prefer to take things S L O W L Y and after four years, my levels still have not hit the "normal" levels I should be at. They think because of my age I should be at a post-menopausal range when I am still trying to get through puberty.
My new Gynecologist and I will have a long discussion next month. I might have to tell her I want to meet with a lactation consultant to see how she would modify my hormone protocol to induce lactation in 9 months. She can't argue that it can't be done. It already has. A transgender woman breastfed her partner's infant successfully for six months before switching to formula. It was all over the news back in 2017.
