Community Conversation => Transitioning => Hormone replacement therapy => Topic started by: KateConnors on August 02, 2011, 12:42:27 PM Return to Full Version
Title: Prometrium as an anti-androgen
Post by: KateConnors on August 02, 2011, 12:42:27 PM
Post by: KateConnors on August 02, 2011, 12:42:27 PM
Hi,
I'm new here, just posted my intro elsewhere......
Anyway, I'm a few months into HRT, and my PCP suggested to me last week that I switch from the estradiol + spiro combination to estradiol + prometrium. I was expected to start prometrium, as I understand the benefit that progesterone can have, especially in the growth phases of being on HRT. What I didn't know about though was that prometrium would negate the need for the spiro? My PCP tells me it's an effective anti-androgen, and she is experienced with trans issues (she's post-op herself and has many trans patients). Is she correct here, or should I be pushing to have my spiro prescription restored?
Thanks!
Kate.
I'm new here, just posted my intro elsewhere......
Anyway, I'm a few months into HRT, and my PCP suggested to me last week that I switch from the estradiol + spiro combination to estradiol + prometrium. I was expected to start prometrium, as I understand the benefit that progesterone can have, especially in the growth phases of being on HRT. What I didn't know about though was that prometrium would negate the need for the spiro? My PCP tells me it's an effective anti-androgen, and she is experienced with trans issues (she's post-op herself and has many trans patients). Is she correct here, or should I be pushing to have my spiro prescription restored?
Thanks!
Kate.
Title: Re: Prometrium as an anti-androgen
Post by: caitlin_adams on August 03, 2011, 06:26:40 AM
Post by: caitlin_adams on August 03, 2011, 06:26:40 AM
Interesting, I hadnt heard of prometrium.
Title: Re: Prometrium as an anti-androgen
Post by: LilKittyCatZoey on August 03, 2011, 06:32:02 AM
Post by: LilKittyCatZoey on August 03, 2011, 06:32:02 AM
If prometrium is a progesterone then no because you need something like spiro to cut down your testosterone to allow Your e and p to work :)
Title: Re: Prometrium as an anti-androgen
Post by: AbraCadabra on August 03, 2011, 07:49:30 AM
Post by: AbraCadabra on August 03, 2011, 07:49:30 AM
Prometrium (generic: Endogest, or Utrogestan) is 'Micronised Bio-Identical Progesterone".
Provera (medroxyprogesterone acetate) is something different AND stronger, synthesised progestine, and THAT is used as an AA.
It also blocks E to some degree by the way.
The diff. is something like between estradiol (17β-estradiol), and ethinyl-estradiol (EE),
Axelle
Provera (medroxyprogesterone acetate) is something different AND stronger, synthesised progestine, and THAT is used as an AA.
It also blocks E to some degree by the way.
The diff. is something like between estradiol (17β-estradiol), and ethinyl-estradiol (EE),
Axelle
Title: Re: Prometrium as an anti-androgen
Post by: KateConnors on September 15, 2011, 04:06:54 AM
Post by: KateConnors on September 15, 2011, 04:06:54 AM
Just an update on this. I spoke with my PCP / GP regarding my concerns on not having Spiro as well as Estradiol and Prometrium, and that only the synthetic progesterone act as an anti-androgen. She admitted that she'd never looked into the difference and was happy to put me on all three. :)
Thanks for the advice.
Thanks for the advice.
Title: Re: Prometrium as an anti-androgen
Post by: AbraCadabra on September 15, 2011, 05:53:21 AM
Post by: AbraCadabra on September 15, 2011, 05:53:21 AM
Good for you Kate, and happy to hear :-)
Axelle
Axelle