Community Conversation => Transitioning => Hormone replacement therapy => Topic started by: Missadventure on March 17, 2014, 06:46:31 PM Return to Full Version
Title: Injection issues?
Post by: Missadventure on March 17, 2014, 06:46:31 PM
Post by: Missadventure on March 17, 2014, 06:46:31 PM
So last friday was my day for giving myself my shot of Delestrogen. I administered it into my right thigh.
Sunday night I noticed my right leg from the knee down, and my right foot, were VERY swollen. No pain, redness, numbness, or anything else. The only reason I noticed is because I was trying on shoes and was like "When the hell did I get cankles?!?!" So, for all I know its been like that since friday night.
Needless to say, my first thought was DVT, and I went into panic mode, but, for reasons too complex and totally off topic I wasn't able to go to the hospital about it.
So I decided to take a wait and see approach. I know DVT actually happens quite frequently, and something like 40% of the affected people never know, and the body naturally takes care of the clot on its own. So. I figured, so long as there's no pain, I'd be okay.
Today the swelling had gone down considerably. It's still there, but barely noticeable. But this afternoon the spot where I administered the injection started to hurt, and the muscle the shot went into is really sore.
So... I'm still feeling concerned, but I'm afraid to go to the hospital (no insurance or employment = no frivolous trips to health care providers).
What I'm wondering is if it could be possible that rather than DVT there could be something more directly related to the injection going on? an infection perhaps? an allergic reaction? etc?
Anyone else ever have any similar experiences?
I dunno. Tomorrow I think I'm going to go to a free clinic just to be safe. But. Hearing stories from others in the meantime can help alleviate a lot of the "OH MY GOD I COULD WAKE UP DEAD" that's running around in my head.
Sunday night I noticed my right leg from the knee down, and my right foot, were VERY swollen. No pain, redness, numbness, or anything else. The only reason I noticed is because I was trying on shoes and was like "When the hell did I get cankles?!?!" So, for all I know its been like that since friday night.
Needless to say, my first thought was DVT, and I went into panic mode, but, for reasons too complex and totally off topic I wasn't able to go to the hospital about it.
So I decided to take a wait and see approach. I know DVT actually happens quite frequently, and something like 40% of the affected people never know, and the body naturally takes care of the clot on its own. So. I figured, so long as there's no pain, I'd be okay.
Today the swelling had gone down considerably. It's still there, but barely noticeable. But this afternoon the spot where I administered the injection started to hurt, and the muscle the shot went into is really sore.
So... I'm still feeling concerned, but I'm afraid to go to the hospital (no insurance or employment = no frivolous trips to health care providers).
What I'm wondering is if it could be possible that rather than DVT there could be something more directly related to the injection going on? an infection perhaps? an allergic reaction? etc?
Anyone else ever have any similar experiences?
I dunno. Tomorrow I think I'm going to go to a free clinic just to be safe. But. Hearing stories from others in the meantime can help alleviate a lot of the "OH MY GOD I COULD WAKE UP DEAD" that's running around in my head.
Title: Re: Injection issues?
Post by: KayXo on March 17, 2014, 08:11:46 PM
Post by: KayXo on March 17, 2014, 08:11:46 PM
Most likely due to the actual injection done there, you hit a vein or something. Doing it in the butt area, outer upper quadrant, reduces the occurrence of such problems. Less painful, less likely to cause complications. It could also be an allergy in which case switching oil, solvant, or preservative could help.
In any case, you should have it checked out as soon as possible.
Injections do not increase DVT risks. Prostate cancer patients are injected very high doses, far higher (and I mean really high!) than typically prescribed to transsexual women...and studies have found no increase in DVT and that is because the estrogen goes directly into the blood, thus very little eventually makes it to the liver...and besides, bioidentical estradiol weakly affects clotting in comparison to other forms such as Premarin and especially Ethinyl Estradiol contained in birth control pills.
In any case, you should have it checked out as soon as possible.
Injections do not increase DVT risks. Prostate cancer patients are injected very high doses, far higher (and I mean really high!) than typically prescribed to transsexual women...and studies have found no increase in DVT and that is because the estrogen goes directly into the blood, thus very little eventually makes it to the liver...and besides, bioidentical estradiol weakly affects clotting in comparison to other forms such as Premarin and especially Ethinyl Estradiol contained in birth control pills.
Title: Re: Injection issues?
Post by: Missadventure on March 17, 2014, 08:28:07 PM
Post by: Missadventure on March 17, 2014, 08:28:07 PM
Quote from: KayXo on March 17, 2014, 08:11:46 PM
Most likely due to the actual injection done there, you hit a vein or something. Doing it in the butt area, outer upper quadrant, reduces the occurrence of such problems. Less painful, less likely to cause complications. It could also be an allergy in which case switching oil, solvant, or preservative could help.
In any case, you should have it checked out as soon as possible.
Injections do not increase DVT risks. Prostate cancer patients are injected very high doses, far higher (and I mean really high!) than typically prescribed to transsexual women...and studies have found no increase in DVT and that is because the estrogen goes directly into the blood, thus very little eventually makes it to the liver...and besides, bioidentical estradiol weakly affects clotting in comparison to other forms such as Premarin and especially Ethinyl Estradiol contained in birth control pills.
Thanks. That's useful information and reduces the amount of panic immensely!
Title: Re: Injection issues?
Post by: Cindy Stephens on March 18, 2014, 10:24:55 AM
Post by: Cindy Stephens on March 18, 2014, 10:24:55 AM
I inject both E and p. The E is in oil and the P is in an aqueous solution. I have never had a problem with injection the P into my thigh, but have with the E. I got weakness and really lost the ability to walk any distance. I always do it in the butt. Only have a problem if I do it too fast. The problem there is doing it while standing up, looking in the mirror. The left side is worse is you are right handed. Practice, practice, practice.
Title: Re: Injection issues?
Post by: KayXo on March 18, 2014, 04:01:06 PM
Post by: KayXo on March 18, 2014, 04:01:06 PM
What is the name of the progesterone you take? Gestone, Proluton-Depot?
Title: Re: Injection issues?
Post by: Missadventure on March 18, 2014, 05:07:36 PM
Post by: Missadventure on March 18, 2014, 05:07:36 PM
Quote from: KayXo on March 18, 2014, 04:01:06 PM
What is the name of the progesterone you take? Gestone, Proluton-Depot?
Me? My progesterone is pill form. Generic prometrium. The walgreens bottle says the manufacturer is Watson.
Title: Re: Injection issues?
Post by: KayXo on March 18, 2014, 05:09:48 PM
Post by: KayXo on March 18, 2014, 05:09:48 PM
I meant Cindy's...hehe. ;) But thanks anyways. :)
Title: Re: Injection issues?
Post by: KayXo on March 18, 2014, 05:24:28 PM
Post by: KayXo on March 18, 2014, 05:24:28 PM
Looking through her posts, I got my answer. She is taking medroxyprogesterone acetate. This is not progesterone but it is a progestin with similar progestogenic properties.
I think it would be important to specify this as side-effects from both are quite different, as evidenced by years of research and studies on both.
I think it would be important to specify this as side-effects from both are quite different, as evidenced by years of research and studies on both.
Title: Re: Injection issues?
Post by: Just Shelly on March 18, 2014, 11:33:55 PM
Post by: Just Shelly on March 18, 2014, 11:33:55 PM
^^^^^pretty much what they said^^^^^
But I do I think it could be either the caster oil or even peanut oil it is compounded with...you may be having an allergic reaction to it.
Though I don't necessarily agree with injecting in the butt....its made to be administered in a muscle and much could be wasted if it is injected into the fat on the butt.
I've been injecting for over 2 years now and do it every week, I never had anything like this....but I have been sore a couple of times...probably nicked a vein.
I'm pretty much a pro at it now....but it still sucks!!!
But I do I think it could be either the caster oil or even peanut oil it is compounded with...you may be having an allergic reaction to it.
Though I don't necessarily agree with injecting in the butt....its made to be administered in a muscle and much could be wasted if it is injected into the fat on the butt.
I've been injecting for over 2 years now and do it every week, I never had anything like this....but I have been sore a couple of times...probably nicked a vein.
I'm pretty much a pro at it now....but it still sucks!!!
Title: Re: Injection issues?
Post by: Missadventure on March 18, 2014, 11:45:10 PM
Post by: Missadventure on March 18, 2014, 11:45:10 PM
Quote from: Just Shelly on March 18, 2014, 11:33:55 PM
^^^^^pretty much what they said^^^^^
But I do I think it could be either the caster oil or even peanut oil it is compounded with...you may be having an allergic reaction to it.
Though I don't necessarily agree with injecting in the butt....its made to be administered in a muscle and much could be wasted if it is injected into the fat on the butt.
I've been injecting for over 2 years now and do it every week, I never had anything like this....but I have been sore a couple of times...probably nicked a vein.
I'm pretty much a pro at it now....but it still sucks!!!
As of today the swelling has, THANKFULLY, gone down. The muscle I injected into is still sore, and there's a bruise now around the injection site... So, that pretty much confirms for me that it had something to do with the injection. Next dose will be definitely going into another location in the body. If it happens again, I can assume it's probably a reaction to the castor oil and other junk in there. And if it doesn't happen again, the I probably just somehow mussied myself up good when I gave myself the injection.
Either way, as of right now, the fact that it's not DVT is causing me to breath huge sighs of relief! :D
Title: Re: Injection issues?
Post by: KayXo on March 19, 2014, 09:02:06 AM
Post by: KayXo on March 19, 2014, 09:02:06 AM
Quote from: Just Shelly on March 18, 2014, 11:33:55 PMThough I don't necessarily agree with injecting in the butt....its made to be administered in a muscle and much could be wasted if it is injected into the fat on the butt.
To avoid this, needle needs to be at least 30 mm or 1 1/4", ideally 1 1/2" inches long (40 mm). Butt is usually less painful than thigh.
If it reaches fat, it will not be wasted but it will be absorbed quicker in blood and thus duration of lifetime of estrogen in blood will be much shorter with much higher peaks. Not good, indeed. :(