Community Conversation => Transitioning => Hormone replacement therapy => Topic started by: nanjana on April 15, 2014, 08:39:17 AM Return to Full Version

Title: sublingual estradiol?
Post by: nanjana on April 15, 2014, 08:39:17 AM
Hi everyone, not sure if this is going against forum rules but I like to hear everyone's viewpoints and not just the medical professionals. I've been prescribed this estradiol



as well as the normal spiro tablets.

So from what I understand, sublingual means under the tongue? I've also researched that it is more effective as it bypasses the liver. So I'm wondering if this is the pill that I can put under the tongue or was there another type of pill?
Title: Re: sublingual estradiol?
Post by: Jessika Lin on April 15, 2014, 10:23:33 AM
You can take it either way (assuming your E is a micronized form) so swallowing it isn't 'wrong' per se, it's just less effective. Taking your E sublingually is more effective since it goes directly into your bloodstream bypassing the liver and the complications that can be caused when the liver processes hormones.
Title: Re: sublingual estradiol?
Post by: nanjana on April 15, 2014, 11:56:30 AM
I don't know what micronized means but it's the circular, little, blue-green hard tablets with watson 488 imprinted on it that becomes powdery when I do it sublingually

Would breaking the pills into 1mg quantities and taking them sublingually throughout the day be better than just taking all the prescribed amount at once?

Also I think a mod censored out the link to the perfectly legal info site that shows the pill :(
Title: Re: sublingual estradiol?
Post by: KayXo on April 15, 2014, 03:27:31 PM
Sublingually, levels tend to rise and fall quite quickly so that it's usually advised to take it several times daily.
Title: Re: sublingual estradiol?
Post by: Dani on April 16, 2014, 05:43:37 PM
Ladies,

I am also taking estradiol sublingually. The Watson brand dissolves very fast and in 10 minutes I feel no tablet residue under my tongue.

The medical literature reports that taking estradiol sublingual as opposed to oral use is up to 20 times more effective in absorption in to the blood stream. The down side is that in 8 to 12 hours, you are back to normal blood levels.