Community Conversation => Transitioning => Hormone replacement therapy => Topic started by: MelissaRC on June 29, 2015, 05:18:13 PM Return to Full Version
Title: spironolactone and ARB drugs
Post by: MelissaRC on June 29, 2015, 05:18:13 PM
Post by: MelissaRC on June 29, 2015, 05:18:13 PM
I have been on estradiol for about 45 days, and thinking about adding an anti-androgen like spironolactone. However, I also have high-blood pressure (very well controlled) and take an ARB (Losartan) and mild beta blockers. I am tolerating the estradiol well, but wonder if there might be an interaction in between the spiro and ARB?
Is anyone out there on a similar combination?
(and, yes, I will see a doc soon ...)
Is anyone out there on a similar combination?
(and, yes, I will see a doc soon ...)
Title: Re: spironolactone and ARB drugs
Post by: Mariah on June 29, 2015, 05:36:35 PM
Post by: Mariah on June 29, 2015, 05:36:35 PM
Hi Melissa, welcome to Susan's. We have no way of knowing for sure if it is or isn't. Obviously you must be having an issue of some kind that you feel needs addressing. I would take that up with your doctor. I look forward to seeing you around the forums. Good luck and Hugs
Mariah
Mariah
Things that you should read
Site Terms of Service & Rules to Live By (https://www.susans.org/forums/index.php/topic,2.0.html) | Standard Terms & Definitions (https://www.susans.org/forums/index.php/topic,54369.0.html) | Post Ranks (including when you can upload an avatar) (https://www.susans.org/forums/index.php/topic,114.0.html.) |
Reputation rules (https://www.susans.org/forums/index.php/topic,18960.0.html) | News posting & quoting guidelines (https://www.susans.org/forums/index.php/topic,174951.0.html) | Photo, avatars, & signature images policy (https://www.susans.org/forums/index.php/topic,59974.msg383866.html#msg383866) |
Title: Re: spironolactone and ARB drugs
Post by: Rachel on June 29, 2015, 05:51:31 PM
Post by: Rachel on June 29, 2015, 05:51:31 PM
I can not answer your question but welcome to Susan's.
Title: Re: spironolactone and ARB drugs
Post by: katrinaw on June 29, 2015, 06:12:49 PM
Post by: katrinaw on June 29, 2015, 06:12:49 PM
Welcome to Susan's Melissa
Sorry I can't answer your Q either, however your Dr or Endo will be able to help you.
I think, i recall, that Spiro does help in Oedema related issues, not sure about its effect on BP tho.
Look forward to seeing you about.
L Katy :-*
Sorry I can't answer your Q either, however your Dr or Endo will be able to help you.
I think, i recall, that Spiro does help in Oedema related issues, not sure about its effect on BP tho.
Look forward to seeing you about.
L Katy :-*
Title: Re: spironolactone and ARB drugs
Post by: .Christy on June 29, 2015, 09:22:57 PM
Post by: .Christy on June 29, 2015, 09:22:57 PM
Hyperkalemia and hypotension may occur depending on the dose ur doc starts u out on.
Title: Re: spironolactone and ARB drugs
Post by: Randi on June 30, 2015, 02:06:33 PM
Post by: Randi on June 30, 2015, 02:06:33 PM
Simply Google, "Drug Interactions" or "Drug interaction checker" and you will find several sites that will provide the answers to your question.
"losartan oral + spironolactone oral
losartan oral and spironolactone oral both increase potassium levels in the blood"
"losartan oral + spironolactone oral
losartan oral and spironolactone oral both increase potassium levels in the blood"
Title: Re: spironolactone and ARB drugs
Post by: Eva Marie on June 30, 2015, 03:42:24 PM
Post by: Eva Marie on June 30, 2015, 03:42:24 PM
My endo has prescribed both spiro and Losartan for me since I have high BP. Of course I'm on estrogen and progesterone too, also prescribed by him. So far nothing has rotted off [emoji1]
Title: Re: spironolactone and ARB drugs
Post by: fairview on July 01, 2015, 12:17:02 PM
Post by: fairview on July 01, 2015, 12:17:02 PM
I'm taking both the lostran and Spiro by rx. Doctor had no problem. That combo finally got me down to a healthy bp and eliminated the fluid build up I always had in my ankles.
Also for some weird reason when I started the Spiro the second night I started sleeping like a rock. No more sleeping pills. Put my head on the pillow and 5 minutes later I'm asleep. Since the Spiro I've never had to watch my alarm clock tick into the next day. Strange.
Also for some weird reason when I started the Spiro the second night I started sleeping like a rock. No more sleeping pills. Put my head on the pillow and 5 minutes later I'm asleep. Since the Spiro I've never had to watch my alarm clock tick into the next day. Strange.
Title: Re: spironolactone and ARB drugs
Post by: KayXo on July 03, 2015, 09:31:33 AM
Post by: KayXo on July 03, 2015, 09:31:33 AM
Spironolactone is known to reduce blood pressure (and water retention).
Title: Re: spironolactone and ARB drugs
Post by: Mariah on July 04, 2015, 04:00:08 PM
Post by: Mariah on July 04, 2015, 04:00:08 PM
:police:
Ok folks lets please keep on topic. I just had to delete a string of posts that caused the thread to completely derailed. Thanks
Mariah
Ok folks lets please keep on topic. I just had to delete a string of posts that caused the thread to completely derailed. Thanks
Mariah
Title: Re: spironolactone and ARB drugs
Post by: iKate on July 07, 2015, 09:01:53 AM
Post by: iKate on July 07, 2015, 09:01:53 AM
Before I started HRT I was on Lotrel (amlodipine-benazepril) which is a combo ACEI and calcium channel blocker. It was OK but not that effective.
They took me off the benazepril and replaced it with Spiro as part of the HRT and a blood pressure medication. My blood pressure gradually improved so much that now they may take me off the amlodipine entirely. I did some lifestyle change and weight loss too.
They took me off the benazepril and replaced it with Spiro as part of the HRT and a blood pressure medication. My blood pressure gradually improved so much that now they may take me off the amlodipine entirely. I did some lifestyle change and weight loss too.