Susan's Place Transgender Resources

i have second question..
is there any T blockers that thay permeant the T for life..after awhile ago?

thanks
Nat'

I answered no because AFAIK, there is no such medication. Taking estrogen is the only way to go. As regards to the second question, not sure. If say, you are on an anti-androgen for 5-6 yrs and stop it...does T rise back up? Maybe but the levels might be less than they were originally, maybe the testes have atrophied to such an extent that they can't recover. It could depend on several factors like the dose taken, the individual in question.

Getting fatter will increase aromatase because it's an enzyme found abundantly in fatty tissue but your health would be compromised and I don't think that would be wise to do especially considering this increase wouldn't make such a big difference anyways. Think of men who are obese.

A doctor will be able to advise you on what is the best route to follow to achieve your goals. Best of luck. :)

Hi Nat'

Welcome to the site.

I haven't the foggiest idea. Sorry. However, you do have one reply and I know we have some other people with a decent amount of knowledge of such info.

I also want to share some links with you. They are mostly welcome information and the rules that govern the site. If you have not had a chance to look through them, please take a moment to:

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Once again, welcome to Susan's. Look around, ask questions and join in.

With warmth,

Joanna

Quote from: wannabetransgendergirl on February 02, 2017, 05:58:25 AM
i have second question..
is there any T blockers that thay permeant the T for life..after awhile ago?

thanks
Nat'

Hi Nat'

Nice poll and question, I think it may relate to the current understanding that ovaries convert testosterone to estrogen via aromatase?

Unfortunately medical science hasn't quite got the method down yet.

It may be related to the basic structure of our DNA, and how that works in full has only been examined in small detail.

Have you ever thought of being a scientist in order to find out?

Basically one free molecule of aromatase enzyme in the blood will convert one molecule of testosterone to estradiol when they bump into each other. Aromatase is produced by fat cells and the pituitary. In cis women the ovaries produce it in the production of estradiol. Testosterone is the previous step in the process. So ovaries produce testosterone and aromatase in essentially equal quantities in the same basic location so the testosterone molecules are almost all converted before release into the bloodstream.

No there is no commercial product to increase aromatase production. There are medications for which increased aromatase is a potential side effect. Specifically cholesterol drugs, anti anxiety, anti depression, and a few anti psychotics.


Interestingly there has been some studies showing the ability of a substance that can turn off the gene in ovaries that produces the aromatase and causes ovaries to turn out just testosterone instead.

Just last night, I read that alcohol can also increase aromatase, hence slightly increasing estrogen concentrations. It was a study in women. Also, spironolactone, an anti-androgen, appears to increase peripheral conversion of androgen to estrogen, albeit to a very slight extent.