Susan's Place Transgender Resources

Hello all...I am pretty sure this has been asked before but oh well...To anyone on IM  estradiol who has tried injecting into the thigh vs the glutes have you noticed a difference in rate of absorption?  I have read that thigh injections burn off quicker and glutes release slower. Has anyone who has done both noticed a difference in bloodwork results?  I currently inject weekly into my thigh area.

I inject into my thighs too.  I will be watching this with interest, as I've never heard of it being a slower release in the glutes.

It's true that the glutes have a slower release. I have not done both but there is research. I have seen a chart somewhere showing the absorption rate at various injection sites for EV. If I can find it, I will post a link.

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Well considering its hard to reach around to my butt and stab myself with a needle (without screwing up).. I inject my thighs too. Works fine for me..

I always injected in my glutes, never in my thighs. Absorption is quite rapid in my case.

I'm a thigh girl.  I like to inject after my 5k run.  My thigh muscle seems easier to slide the needle into at that point.  Maybe that affects the absorption, too?  Curious...

The reason why I ask is I have read multiple articles that the glute area is the slowest release.  From what I read it goes glute, thigh, then deltoid from slowest to fastest.  And for me so far  when I was injecting into my thigh area I would get this rush of nausea within about few hours of the shot which also makes me think my body was absorbing it to fast.  Last time I had my level of estradiol checked it was sky high at 1889pg/ml and that was like a day after the injection into the thigh.  I have many questions many questions.

I had not heard any of that.  I guess it might matter.  I have been on the shots so long that the only effect I feel from it anymore is I get weepy/emotional the day after I inject.  My eyes well up with tears over the dumbest things.  But, I have never felt nausea.

Quote from: ainsley on June 05, 2017, 01:51:29 PM
I had not heard any of that.  I guess it might matter.  I have been on the shots so long that the only effect I feel from it anymore is I get weepy/emotional the day after I inject.  My eyes well up with tears over the dumbest things.  But, I have never felt nausea.

I agree with that these shots do get me "up in my feelings" a little more

Quote from: mako9802 on June 05, 2017, 01:56:49 PM
I agree with that these shots do get me "up in my feelings" a little more

Yes!  Part of the female experience, as my wife tells me.  (She's like "Welcome to it!")

Just an update.  It has been 3 weeks since I changed my injection location from the thigh to the hip area.  I dont know if it is psychsomatic but I do feel different on this location.  My chest has been itching way more than it has  been.  I dont know if this would have happened regardless and I wont have levels checked till next month but it does appear to make a difference at least in my case.

I get my estradiol dose from taking a pill sublingually twice per day.

Can someone explain the advantage injections have over taking the pill?

This has been on my mind lately.

Advantages:

1) one injection weekly vs having to take the pill twice daily sublingually
2) can get higher levels for a longer time but does not necessarily translate into better results
3) in some cases, cheaper $$$

I had better breast development on pills but feel better and skin/hair is glowing on injections, feminization overall seems improved too.

I am a sublingual girl as well.

I just do not like needles.

Lets start a new thread, so we do not hijack this one.

When I first started I did pills and they made me very nauseous.  So the doctor switched me to injections. I've never been nauseous with the shots. When I started injections I self injected into my thighs but it always hurt. For me anyway. So my brother started doing it for me in my backside and it doesn't hurt at all. I didn't notice any difference but I was only doing thigh injections for the first month.

Quote from: Dani on June 15, 2017, 09:36:18 AM
I am a sublingual girl as well.

I just do not like needles.

Lets start a new thread, so we do not hijack this one.

New thread, as requested. ;)

https://www.susans.org/forums/index.php/topic,224884.new.html#new