Community Conversation => Transitioning => Hormone replacement therapy => Topic started by: mako9802 on July 25, 2017, 03:16:40 PM Return to Full Version

Title: Can too high of an estradiol level impede progress?
Post by: mako9802 on July 25, 2017, 03:16:40 PM
I have always wondered this?  I know SHBG binds sex hormones such as DHT, and Testosterone but how much does SHBG bind estradiol?  Just like we have free testosterone we have free estradiol levels.
Title: Re: Can too high of an estradiol level impede progress?
Post by: TinaVane on July 25, 2017, 04:16:57 PM
Hhhmmmmm


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Title: Re: Can too high of an estradiol level impede progress?
Post by: KayXo on July 25, 2017, 10:00:49 PM
I had poor breast development on very high levels with injections and much better results on oral and gel where levels were lower, and this despite even adding some T to the mix. BUT, I think the reason for poor breast development on injections might be due to levels falling to rapidly whereas with oral/gel, they remained more constant. Who knows?