Susan's Place Transgender Resources

Has anyone had  any experience  with being on a certain dosage of spiro for  a period of time then reducing the dose  where that had a negative effect  on their progress. I recently had a followup visit with  my doctor and  we discussed  this I just wanted to get some  opinions  from the field.  My T levels have  been totally nuked from the doses  I have been taking, last time my T was  at like 7ng/dl...but here recently I have felt like zero motivation to do anything.  For the  record I take estradiol  valerate injections every 5 days, and  spiro, and prometruim,   and dutasteride. 

With my doctor aware I reduced my spiro by half many months ago. His only concern was that my hair regrowth may increase but I have not seen any sign of that. My T was checked about 2 months ago and it was about where yours is. I also take oral estradiol and progesterone. I have noticed no problems. As a result he reduced my prescription to the lower amount I am taking.

If you have been on Estradiol for a year or two, that alone will suppress your Testosterone blood levels without Spironolactone. Your Endocrinologist can order hormone blood tests to see where your hormone levels are. It is always a good idea to take the least amount of all drugs that will still get you where you want to be.

Yes, an estradiol-only protocol is workable, I've been doing it for about 2 years now. It will require a minimum E level, which I won't mention here as it seems to cause some members here to have a stroke. It's not really that high and you are probably already there based on what you've said. The lack of motivation/energy is almost certainly caused by a lack of T.

More and more doctors are moving away from prescribing antiandrogens, as with current forms of estradiol, they really aren't needed for most people.

I was on cyproterone, but discontinued use due to side effects. Too late as it turns out, I'm now the proud owner of a meningioma. Thanks, doc.

Quote from: PurplePelican on November 19, 2018, 01:19:59 AM
Yes, an estradiol-only protocol is workable, I've been doing it for about 2 years now. It will require a minimum E level, which I won't mention here as it seems to cause some members here to have a stroke. It's not really that high and you are probably already there based on what you've said. The lack of motivation/energy is almost certainly caused by a lack of T.

More and more doctors are moving away from prescribing antiandrogens, as with current forms of estradiol, they really aren't needed for most people.

I was on cyproterone, but discontinued use due to side effects. Too late as it turns out, I'm now the proud owner of a meningioma. Thanks, doc.

Hi, hope you don't mind me asking, but why are doctors prescribing antiandrogens less and less?

I'm on Spironactone almost a year now and help normal my Potassium level, and it allows my Endocrine increase my Estradiol medications.

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Quote from: veronicashannon88 on November 20, 2018, 09:52:29 PM
Hi, hope you don't mind me asking, but why are doctors prescribing antiandrogens less and less?

Mostly due to the fact that most trans women don't need them. A sufficient E level is enough to suppress gonadal T without impacting adrenal T levels. Other areas of medicine have or are also moving away from them.

Quote from: Meghan on November 21, 2018, 12:55:36 AM
I'm on Spironactone almost a year now and help normal my Potassium level, and it allows my Endocrine increase my Estradiol medications.

If it's helping your potassium level, then you must have low potassium, as spironolactone is known to cause high potassium. It is also completely unrelated to what dose of E you might be given - especially when you consider that a sufficient level of E makes spiro unneeded.

I was borderline high in Potassium and Spironactone help reduce my Potassium to ok level. Now I'm not tired or exhaust so often anymore.

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