Community Conversation => Transgender talk => Topic started by: Hinoiri on August 15, 2025, 05:29:36 PM Return to Full Version

Title: Estradiol and sleeping
Post by: Hinoiri on August 15, 2025, 05:29:36 PM
I have a question. I take my estradiol at bedtime with my snacks and cup of hot tea. I have noticed taking estradiol is making me a little sleepier than the normal before taking. Anyone else is affected this way? Also do you take your hormone at a different time? Not complaining just curious.
Title: Re: Estradiol and sleeping
Post by: Lori Dee on August 15, 2025, 05:56:15 PM
Quote from: Hinoiri on Yesterday at 05:29:36 PMI have a question. I take my estradiol at bedtime with my snacks and cup of hot tea. I have noticed taking estradiol is making me a little sleepier than the normal before taking. Anyone else is affected this way? Also do you take your hormone at a different time? Not complaining just curious.

I didn't have that happen with estradiol, but progesterone does. Known side effects of progesterone are dizziness and drowsiness, which is why it is often prescribed before bedtime. Over time, the body adjusts to it, so maybe you are still adjusting.
Title: Re: Estradiol and sleeping
Post by: Alana Ashleigh on August 15, 2025, 06:32:38 PM
 When I taking estradiol orally, I took it in the early afternoon right before I got to work. I never experienced any sleepiness from it.
Title: Re: Estradiol and sleeping
Post by: KathyLauren on August 15, 2025, 07:26:33 PM
I take my estradiol by bi-weekly patches, so daily timing is not an issue.  I think that, on the whole, I sleep better than I used to in the bad old days.  However, I often get a hot flash at 3:30 - 4:00 am which wakes me up.  No idea what that is about.
Title: Re: Estradiol and sleeping
Post by: Lori Dee on August 15, 2025, 08:51:03 PM
Quote from: KathyLauren on Yesterday at 07:26:33 PMHowever, I often get a hot flash at 3:30 - 4:00 am which wakes me up.

I had that issue with patches, too. Labs showed my levels were too low. Hormone levels fluctuate throughout the day. Your body has a threshold. Above that, and you are good. But if you are close, then any drop below the threshold, even momentarily,  and you get the PMS symptoms (hot flashes, night sweats, etc.) Once I got my levels high enough so that the lows were still above the threshold, all that disappeared. Maybe get your levels checked and just see what they say.  :)