News and Events => Science & Medical News => Topic started by: Natasha on October 14, 2008, 05:38:06 PM Return to Full Version
Title: New insights into SRY regulation through identification of 5' conserved sequence
Post by: Natasha on October 14, 2008, 05:38:06 PM
Post by: Natasha on October 14, 2008, 05:38:06 PM
New insights into SRY regulation through identification of 5' conserved sequences
http://7thspace.com/headlines/295176/new_insights_into_sry_regulation_through_identification_of_5_conserved_sequences.html (http://7thspace.com/headlines/295176/new_insights_into_sry_regulation_through_identification_of_5_conserved_sequences.html)
10/14/2008
SRY is the pivotal gene initiating male sex determination in most mammals, but how its expression is regulated is still not understood. In this study we derived novel SRY 5' flanking genomic sequence data from bovine and caprine genomic BAC clones.
http://7thspace.com/headlines/295176/new_insights_into_sry_regulation_through_identification_of_5_conserved_sequences.html (http://7thspace.com/headlines/295176/new_insights_into_sry_regulation_through_identification_of_5_conserved_sequences.html)
10/14/2008
SRY is the pivotal gene initiating male sex determination in most mammals, but how its expression is regulated is still not understood. In this study we derived novel SRY 5' flanking genomic sequence data from bovine and caprine genomic BAC clones.
Title: Re: New insights into SRY regulation through identification of 5' conserved sequence
Post by: iFindMeHere on November 11, 2008, 08:25:19 PM
Post by: iFindMeHere on November 11, 2008, 08:25:19 PM
What does that mean?
Title: Re: New insights into SRY regulation through identification of 5' conserved sequ
Post by: Seshatneferw on November 12, 2008, 04:31:25 AM
Post by: Seshatneferw on November 12, 2008, 04:31:25 AM
Very roughly, the SRY gene (a small segment of the Y chromosome) is the 'master switch' regarding sex. This study has identified a few other gene sequences that have something to do with determining what happens when that master switch is flipped from 'female' to 'male'. They also suggest that mutations in these might have something to do with intersex conditions where a woman has a Y chromosome.
Nfr
Nfr
Title: Re: New insights into SRY regulation through identification of 5' conserved sequence
Post by: iFindMeHere on November 12, 2008, 09:03:20 AM
Post by: iFindMeHere on November 12, 2008, 09:03:20 AM
thank you for the crayon edition. Now I understand it. :)