Community Conversation => Transitioning => Hormone replacement therapy => Topic started by: melanie2009 on January 01, 2010, 04:02:51 AM Return to Full Version
Title: Does micronized progesterone interfere with Estrogen receptors?
Post by: melanie2009 on January 01, 2010, 04:02:51 AM
Post by: melanie2009 on January 01, 2010, 04:02:51 AM
Ive read som much about the pros and cons of adding a progesterone.
Does micronized progesterone interfere with Estrogen receptors? Does it raise T-levels?
Id appreciate to hear others peoples advice and experience on this.
Melanie
Does micronized progesterone interfere with Estrogen receptors? Does it raise T-levels?
Id appreciate to hear others peoples advice and experience on this.
Melanie
Title: Re: Does micronized progesterone interfere with Estrogen receptors?
Post by: rejennyrated on January 01, 2010, 06:09:31 AM
Post by: rejennyrated on January 01, 2010, 06:09:31 AM
Quote from: melanie2009 on January 01, 2010, 04:02:51 AMAll forms of progesterone will moderate the interaction of estrogen - that is why combined HRT is often referred to as "opposed hormone therapy" in medical journals. So you end up taking a slightly higher dose of E.
Ive read som much about the pros and cons of adding a progesterone.
Does micronized progesterone interfere with Estrogen receptors? Does it raise T-levels?
Id appreciate to hear others peoples advice and experience on this.
Melanie
The point is though that progesterone does other things as well - for exmaple it changes your mood, it has an affect on your osmotic balance and hence blood pressure... etc etc.
My experience after 25 years taking a combined HRT regimen is that the balance of benefits outweighs the cons.
As far as T level are concerned - I don't know - the only thing I do know is that mine are pretty well bang on right for a natal female, (just fractionally low but within the margin of error) which is surely what one should aim for as a very low T level leads to lack of sex drive and all sorts of other problems.
Title: Re: Does micronized progesterone interfere with Estrogen receptors?
Post by: melanie2009 on January 01, 2010, 06:39:02 AM
Post by: melanie2009 on January 01, 2010, 06:39:02 AM
Thanks for the reply. Can you explain to me what you mean by
Melanie
QuoteSo you end up taking a slightly higher dose of E. You mean that whilst on progesterone, the levels of Estrogen have to be increased to compensate.?
Melanie
Title: Re: Does micronized progesterone interfere with Estrogen receptors?
Post by: rejennyrated on January 01, 2010, 08:14:27 AM
Post by: rejennyrated on January 01, 2010, 08:14:27 AM
yes - some people take a very slightly higher dose of estrogen - but really only a very small increase.
And like I say you do need to get an endocrinologist or other medically trained person to design and supervise the program until you know for sure how it is working for your body.
And like I say you do need to get an endocrinologist or other medically trained person to design and supervise the program until you know for sure how it is working for your body.
Title: Re: Does micronized progesterone interfere with Estrogen receptors?
Post by: Autumn on January 05, 2010, 02:43:36 AM
Post by: Autumn on January 05, 2010, 02:43:36 AM
Last time I had my bloodwork done, I was at the height of my P cycle and my T count was still as low as he wanted it. I personally have not been taking extra E while cycling. My breasts seem to be coming along quite well. But of course HRT is a horribly inexact science and everybody's body reacts differently.