Susan's Place Transgender Resources

Community Conversation => Transitioning => Hormone replacement therapy => Topic started by: Hideyoshi on May 24, 2014, 09:04:18 PM

Title: oral estradiol + oral prednisone interactions?
Post by: Hideyoshi on May 24, 2014, 09:04:18 PM
I'm having a pretty awful ulcerative colitis flare up, and my doctor prescribed me prednisone.

I searched online and got mixed information on whether or not prednisone interacts with oral estradiol. Does anybody have any experience with this? Should I just take the prednisone like 6 hours apart from my estradiol to avoid such interactions if they exist?
Title: Re: oral estradiol + oral prednisone interactions?
Post by: Flan on May 25, 2014, 02:13:49 AM
Quoteprednisone + estradiol

    prednisone will decrease the level or effect of estradiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Significant interaction possible, monitor closely.
Just watch the mood for while you're on it to control UC.