Hi Everyone,
I just want to report that I am having some positive results with P including all the side effects that we all know (skin is better- a bit oilier, libido is becoming normal and just overall sense of calmness). However, I am also noticing that I am constantly craving for something so I am always keeping a diary of my food intake in a day to keep it under control.
Also, the girls are getting a bit fuller and heavier and so far my mood has been pretty stable. I used to be so afraid of taking them due to the negative effects reported by some members. However, these are my results and ymmv.
I hope this helps and provide some insight to anyone considering taking them. I suggest go for the micronized P than synthetic. I am currently cycling it 10 days on 20 days off P.
Hugs,
April
This is my second month on it. I'm doing the first 15 days on and the rest off, and probably going to double my dose next month. I've noticed an increased appetite too! But not just cravings, I actually get the tummy grumbles more often and am eating three meals a day instead of two now. My libido has increased too, which is odd and interesting, but making me feel more like my T is up so I'm a bit paranoid about that. I'll have to watch my moods and skin though. I think my scalp has been a bit oilier, because I can't seem to go more than a couple days without washing my hair. Mood is maybe a bit more stable, but sometimes it's hard to tell. Breast growth is a very noticeable change, and they have been hurting and itching a lot more and just feel bigger. Let us know how the next month goes, it's interesting to compare our results. :)
Hi Ashey,
Trust me I was also getting paranoid about the whole libido thing. However, P is known to do that in women and I think it is perfectly normal. I also read in some articles that micronized Progesterone are NOT androgenic and can actually replace your existing AA so I'll be very interested to know my T levels this coming January after my blood work results come out.
Yes, I also get the tummy grumbles and I would normally just have a piece of fruit and a hot tea (i.e. green tea) to sort of put it under control and it's working so far :)
One thing I must say tho that the quality of my sleep is not as good as it was before and I've read that P can sometimes do that.
Keep us posted Ashey xo
Quote from: Ashey on December 02, 2015, 05:00:40 PM
This is my second month on it. I'm doing the first 15 days on and the rest off, and probably going to double my dose next month. I've noticed an increased appetite too! But not just cravings, I actually get the tummy grumbles more often and am eating three meals a day instead of two now. My libido has increased too, which is odd and interesting, but making me feel more like my T is up so I'm a bit paranoid about that. I'll have to watch my moods and skin though. I think my scalp has been a bit oilier, because I can't seem to go more than a couple days without washing my hair. Mood is maybe a bit more stable, but sometimes it's hard to tell. Breast growth is a very noticeable change, and they have been hurting and itching a lot more and just feel bigger. Let us know how the next month goes, it's interesting to compare our results. :)
I take it continuously. I don't see the need to cycle.
Quote from: Ashey on December 02, 2015, 05:00:40 PM
This is my second month on it. I'm doing the first 15 days on and the rest off, and probably going to double my dose next month. I've noticed an increased appetite too! But not just cravings, I actually get the tummy grumbles more often and am eating three meals a day instead of two now. My libido has increased too, which is odd and interesting, but making me feel more like my T is up so I'm a bit paranoid about that. I'll have to watch my moods and skin though. I think my scalp has been a bit oilier, because I can't seem to go more than a couple days without washing my hair. Mood is maybe a bit more stable, but sometimes it's hard to tell. Breast growth is a very noticeable change, and they have been hurting and itching a lot more and just feel bigger. Let us know how the next month goes, it's interesting to compare our results. :)
Tale of the tape for me is that P has definitely increased breast growth. I went from 38" to about 42" circumference very quickly (3 months). My rib cage is 32". I fit 34C but that is getting tight too. And yes, I have stretch marks now. :\
My libido is definitely higher now, like OMG higher. Not in a masculine way either... Like lusting after guys and stuff. I have to behave myself lol.
I am also happy to say that due to P, I am sweating less compared to just taking Estradiol and Spironolactone.
I think it may have to do with P raising your core temperature.
:)
Quote from: April_TO on December 04, 2015, 08:14:18 AM
I am also happy to say that due to P, I am sweating less compared to just taking Estradiol and Spironolactone.
I think it may have to do with P raising your core temperature.
:)
I hadn't noticed. I only sweat when I go to the gym now but I sweat a lot less.
What about hair falling
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I have been on P for a year and no hair has fallen out.
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Quote from: ifonlyican14 on December 05, 2015, 09:48:09 AM
What about hair falling
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I think that is a side effect from MPA and synthetic progestins not bioidentical P.
I have been very, very curious about the results I could possibly get on progesterone.. I talked to my endocrinologist about it but he said he is not a believer of the drug and will not put me on it. Wondering if results of the drug are substantial enough that it warrants a visit to another endo??
It is worth the shot. I'm really liking it so far and the only thing I hate about it the most is my constant craving for food. Other than that I have not seen any androgenic effects on me. I take it every bedtime as it can cause grogginess and fatigue at night. But you'll wake up glowy and happy :icon_chick:
Quote from: Roni on December 05, 2015, 11:46:22 AM
I have been very, very curious about the results I could possibly get on progesterone.. I talked to my endocrinologist about it but he said he is not a believer of the drug and will not put me on it. Wondering if results of the drug are substantial enough that it warrants a visit to another endo??
You can actually get plant derived progesterone as an over the counter cream if thats's something you'd like to try. I don't think this counts as self medicating since progesterone is not known to be dangerous and you can legally buy it without a prescription. Your endo might be upset if you take it without telling them though.
I've been using the Emerta progesterone cream for several months now, and I noticed some real effects from it. Just not the ones I was looking for. :-\ It did increase my energy levels somewhat, which was a positive effect. But it also increased my libido, which is not something I necessarily want to deal with still being pre-op. It was interesting though, because like Kate, it pretty much only increased my attraction to men, even though I identify as bisexual. I've been starting to think lately that even if I am fine with dating someone of either gender in principal, actually dating another girl wouldn't work very well for reasons of sexual compatibility...
I decided to stick it out and see if there were positive physical effects, but so far that has been disappointing too. My breast growth has been stalled for a while now, and adding progesterone didn't seem to make much of a difference. I wonder if it would have helped more if I'd been taking it earlier on while my breasts were growing more actively, but I guess it's too late for that now. :( The good news is that I decided to start cycling the cream for a while to see if that made any difference, and once I stopped using it I started to feel some soreness in my breasts again. I think they might have grown a little since then, but it's hard to tell. I've heard the theory that one of the reasons progesterone can help with breast growth is that it actually competes with estrogen, which can act as a reset switch to keep your breast tissue from getting "used to" your estrogen levels, so that is why it's important to cycle. I was skeptical about that though, since women tend to experience a spurt of breast growth during pregnancy when progesterone levels are consistently high. Anyway, I am going to keep cycling for a while to see if it makes a difference.
I think the progesterone is getting on top of me. Been irritable, felt sick over the weekend, and noticed some breast growth. I mean, I'm not really complaining, it's to be expected, just seems to be really doing something though. My right titty is getting a bit bigger, and my nipple is sticking out even more and is noticeably bigger than the left and has some slight purpleness around it like it's a lil swollen. Guess that's a good thing though. Hope lefty catches up soon though.
Hi, Ashey - I think that's progress :)
My areola has grown and I can see a bit of roundness to the girls as well. It kinda reminds me of pregnant woman's breast. My mood for some reason has been quite stable and I am feeling less anxious. However, I am always hungry and craving food so I am tracking everything and working out almost everyday. I really think P should be an adjunctive therapy along with E and AA combo. It has done wonders for me.
A
Quote from: Ashey on December 07, 2015, 08:10:23 PM
I think the progesterone is getting on top of me. Been irritable, felt sick over the weekend, and noticed some breast growth. I mean, I'm not really complaining, it's to be expected, just seems to be really doing something though. My right titty is getting a bit bigger, and my nipple is sticking out even more and is noticeably bigger than the left and has some slight purpleness around it like it's a lil swollen. Guess that's a good thing though. Hope lefty catches up soon though.
Quote from: April_TO on December 02, 2015, 09:23:08 AM
I hope this helps and provide some insight to anyone considering taking them. I suggest go for the micronized P than synthetic. I am currently cycling it 10 days on 20 days off P.
Hugs,
April
I've heard that it makes sleep come easier, but when you cycle off do you have more trouble sleeping than you used to before you started taking P?
Quote from: April_TO on December 05, 2015, 01:12:50 PM
It is worth the shot. I'm really liking it so far and the only thing I hate about it the most is my constant craving for food. Other than that I have not seen any androgenic effects on me. I take it every bedtime as it can cause grogginess and fatigue at night. But you'll wake up glowy and happy :icon_chick:
androgenic effects are usually from synthetic progestins like medroxyprogesterone acetate, not from bio identical like prometrium.
Quote from: Roni on December 05, 2015, 11:46:22 AM
I have been very, very curious about the results I could possibly get on progesterone.. I talked to my endocrinologist about it but he said he is not a believer of the drug and will not put me on it. Wondering if results of the drug are substantial enough that it warrants a visit to another endo??
It's worth a shot but I think if E is producing nothing your only option may be a BA.
An update: I'm still cycling, first 15 days on.. seems to be working well for me. Doubled the dose this month to what will be my standard dose. I think my skin is maybe a bit softer, but most noticeable my sex drive has gone way up from what it was. Almost feels like my old sex drive has halfway returned... Not sure if that's a good thing or not as I get distracted a lot... My appetite seems to have also gone up, at least when I'm on. And my tits definitely hurt more often and are getting bigger. My right nipple texture and color has changed too. It's maybe a bit darker and redder/browner while the left one is a bit pinker and lighter, though they're not dramatically different. Hard to describe the texture change though, but I suppose it's slightly rougher? Left is also shinier while the right is more matte now, and maybe slightly velvety? Again, hard to describe the texture change but it's even noticeable just looking at it. Overall my mood seems to be pretty good though, and rather stable.
I've been on prometrium for about a year now. Boobs have grown as has my belly and butt. I take it on a 12 day/month cycle per my endo.
It gave me wild emotional rides when i first started taking it but that has leveled off now. I am definitely more emotional during those 12 days though. I am more hungry during those 12 days, but the libido changes others have noticed have been pretty much absent for me. I seem to need more sleep too.
Prometrium has a "cloying" effect on me - after the 12 days i'm more than ready ready to stop taking it.
I like what it's done to my boobs and my butt but not so much my belly. I guess that two out of three isn't bad :)
I am on my 2nd month of cycle and I find that it's also working very well for me. In fact, I have noticed noticeable changes on the texture of my skin and also the continuous swelling of my breast and enlargement of the aerola/nipple.
I also noticed that the contours of my face are getting a lot rounder and hair is getting thicker with P. Hips have gained a bit with most of the fat going to my behind. Libido has increased a bit but not to point that I cannot control it which is a major plus for me.
Overall, I am satisfied and I am currently on a 10 day 20 day off cycle.
April xo
Quote from: April_TO on January 04, 2016, 10:45:50 AM
I am on my 2nd month of cycle and I find that it's also working very well for me. In fact, I have noticed noticeable changes on the texture of my skin and also the continuous swelling of my breast and enlargement of the aerola/nipple.
I also noticed that the contours of my face are getting a lot rounder and hair is getting thicker with P. Hips have gained a bit with most of the fat going to my behind. Libido has increased a bit but not to point that I cannot control it which is a major plus for me.
Overall, I am satisfied and I am currently on a 10 day 20 day off cycle.
April xo
I have noticed a lot of the same too. Everything fits better now. Hips filling out nicely and breast continues to grow and shape nice and round and actually looking like breasts rather than cones. I do feel a bit bloated though. However I just take mine every day as directed. No cycling here.
My hips have gotten bigger too, but I think that's just overall weight gain, but still ridiculous. I went from like 43-44 inches to 47... Glad my pants are stretchy! Lol. Though now I usually just wear denim leggings anyway.
And about the cycling, it's an experiment, like all of this is really.. My endo doesn't know specifics, so I was never told specifically what dose or how many days or what, and I doubt he'd know if I asked. But I do know I have a cycle, so I'm just trying to reason out how progesterone levels are in natural cycles, and it's not constant through the month. Then again, I mean.. maybe the body will increase and decrease it regardless... I know that my e levels are probably going to be different at different points in my cycle, even though I take the same amount each day. So who knows... At least this way I'm saving money, lol.
Mine told me just take it, don't cycle. There is debate about cycling to mimic the menstrual cycle but when you think about it, pregnancy causes a lot of breast development and there is a constant supply of P during that time. Also if you truly want to mimic the menstrual cycle you need to vary your E too.
Either way I'm growing at a good clip now.
Cycles aren't natural as levels increase in the second phase in preparation of pregnancy so naturally, the woman would become pregnant not how it is in our society since the Industrial revolution, with the advent of birth control pills and what not. Most women traditionally spent most their lifetime being pregnant and breastfeeding, much less time cycling. Some posit that so many cycles in a lifetime have contributed to the increase in breast cancers. Nuns have been historically known to be afflicted with this and they only cycle. Cycles also increase risk of mood swings (PMS). No thanks!
I take my progesterone continuously since more than a year. A high dose by comparison which gives me levels ranging from 13-20 ng/dl 12 hours after last dose so imagine the peak?!
I have recently experimented with lowering my dose in half. As a result, I feel less bloated, slight weight loss, definitely sleep better at night, paradoxically. My breasts started to hurt finally, again! and nipples are bigger. Skin *seems* softer, interestingly. Calmer, more stable, less highs and lows. Skin appears less dimply, smoother and more translucent (whiter). I take a high dose of E by injection as well.
Seems like at first, progesterone improves my mood, makes me super happy and relaxed, plenty of energy (too much?) but later, the opposite tends to happen, I have low energy, somewhat depressed (high and low). My face is definitely not oily ever! More on the dry side which seems to improve with less P (?)...to be confirmed. I found my skin and hair improved most when I went from E pills to injections, not when I added P.
On less P, my T was 20 ng/dl. On double the dose, my T was 8 ng/dl. T does not increase with P, it seems.
It is well known that P increases weight gain while E keeps it in check, especially at waist so no belly. That was one of the reasons I cut my dose in half, to see if P was truly the culprit.
Will keep you posted. :)
Have any of you been on estro for a protracted period of time like a few years and then started P? Sorry if it was stated somewhere and I missed it.
I'm interested in any results that are clearly P derived with E based results having peaked. My doc has also dissuaded me from P due to the side effects but my curves need more curving.
I had asked about adding prometrium to my HRT, but my doctor wants to wait to see how I react to low dose over the next few months. I actually do like that she's being cautious, but it is hard being patient sometimes.
Okay so, I'm stopping the prometrium for now. I don't think I'm having a good reaction from doubling my dose.. Past few days things have been getting worse.. My left leg started feeling a bit tender, especially around the knee. Then my lower leg was feeling a bit swollen. Now I'm getting frequent mild pain around me knee and back of my thigh, both my feet feel swollen and tender, and I swear my left arm is occasionally feeling a bit weird, similarly. My feet are also getting a tingly sleepy kinda feeling and occasional mild intermittent pain. Overall, I just feel kinda swollen. So hopefully it's just the dose increase, and stopping will make it go away because I'm kinda scared right now that it's going to be related to blood clots... I won't be taking any more of it until I see my endo again in a few weeks. I'll keep y'all updated over the next few days as I see if stopping it eases the issues...
So sorry to hear that Ashey, I am on month two and so far I have been getting good results. I would definitely check in with your doctor. However, I had the same side effects when I took spiro for the first time.
Are you drinking enough water and are you taking enough salt? My doctor told me that a lack of salt would cause leg pain and soreness. So that will be a good excuse for you to have some chips for the time being :) granting you've checked in with your doctor.
I just finished my cycle and my boobs are definitely bigger and rounder. Quite honestly, I have also gained weight but it seems like my clothes are still fitting me quite ok so I wonder where the extra weight is going lol.
Anyways, thanks for the update and for the lady who asked how long was I on E before taking P - it was shortly after a year.
Best,
April
Quote from: Ashey on January 10, 2016, 04:23:40 AM
Okay so, I'm stopping the prometrium for now. I don't think I'm having a good reaction from doubling my dose.. Past few days things have been getting worse.. My left leg started feeling a bit tender, especially around the knee. Then my lower leg was feeling a bit swollen. Now I'm getting frequent mild pain around me knee and back of my thigh, both my feet feel swollen and tender, and I swear my left arm is occasionally feeling a bit weird, similarly. My feet are also getting a tingly sleepy kinda feeling and occasional mild intermittent pain. Overall, I just feel kinda swollen. So hopefully it's just the dose increase, and stopping will make it go away because I'm kinda scared right now that it's going to be related to blood clots... I won't be taking any more of it until I see my endo again in a few weeks. I'll keep y'all updated over the next few days as I see if stopping it eases the issues...
Thanks for the feedback Kay, always so informative. I'll stick to my cycling for now and see how it goes.
As for my t levels, I am at 30 ng/dl (Testosterone) the last time I did my blood work in November. I am in the middle of the female range so my doctor kept me in a slightly lower dose for Spiro.
I might be switching to CPA, couple with a low dose diuretic to keep the water retention at bay.
Anyways, keep us updated xo
Quote from: KayXo on January 05, 2016, 10:51:06 PM
Cycles aren't natural as levels increase in the second phase in preparation of pregnancy so naturally, the woman would become pregnant not how it is in our society since the Industrial revolution, with the advent of birth control pills and what not. Most women traditionally spent most their lifetime being pregnant and breastfeeding, much less time cycling. Some posit that so many cycles in a lifetime have contributed to the increase in breast cancers. Nuns have been historically known to be afflicted with this and they only cycle. Cycles also increase risk of mood swings (PMS). No thanks!
I take my progesterone continuously since more than a year. A high dose by comparison which gives me levels ranging from 13-20 ng/dl 12 hours after last dose so imagine the peak?!
I have recently experimented with lowering my dose in half. As a result, I feel less bloated, slight weight loss, definitely sleep better at night, paradoxically. My breasts started to hurt finally, again! and nipples are bigger. Skin *seems* softer, interestingly. Calmer, more stable, less highs and lows. Skin appears less dimply, smoother and more translucent (whiter). I take a high dose of E by injection as well.
Seems like at first, progesterone improves my mood, makes me super happy and relaxed, plenty of energy (too much?) but later, the opposite tends to happen, I have low energy, somewhat depressed (high and low). My face is definitely not oily ever! More on the dry side which seems to improve with less P (?)...to be confirmed. I found my skin and hair improved most when I went from E pills to injections, not when I added P.
On less P, my T was 20 ng/dl. On double the dose, my T was 8 ng/dl. T does not increase with P, it seems.
It is well known that P increases weight gain while E keeps it in check, especially at waist so no belly. That was one of the reasons I cut my dose in half, to see if P was truly the culprit.
Will keep you posted. :)
Bio-identical progesterone does NOT affect coagulation hence cannot cause blood clots. This has been confirmed by studies, so no worries. Certain progestins can however increase the risk (i.e. in birth control pills, Provera, etc.). It's important to not put all progestogens in the same basket and be well informed so as not panic for no reason.
Progesterone is also known to be a diuretic like Spiro, both having antimineralocorticoid properties so could be the side-effects were from a lack of water and/or salt intake.
Or could just be that you are anxious since doubling dose because those symptoms can come from anxiety as well.
Kay, Prometrium is a progestin and coupled with the estradiol that I'm taking, can significantly increase the risk of DVT and subsequent pulmonary embolisms. Please don't use disinformation to hand-wave my 'hysteria' away. I also have other risk factors that could contribute. The anxiety came after my feet had swollen and my legs had had pain for a few days. Anyway, even since I stopped taking it the other day, my legs are a lil better. Still a bit sore but my feet aren't swollen or tingly, and my legs are at the point where I can walk fine and not freak out. So I think if I go back on it, maybe I'll stick with my previous dose since I didn't seem to have problems with that.
Quote from: Ashey on January 11, 2016, 04:35:29 PM
Kay, Prometrium is a progestin and coupled with the estradiol that I'm taking, can significantly increase the risk of DVT and subsequent pulmonary embolisms.
Scientifically speaking, Prometrium (bio-identical micronized progesterone) is not a progestin but a progestogen. Progestins are any form of progestogen that is not bio-identical.
Contraception. 1987 Oct;36(4):373-402."No side effects have been reported as far as lipids profile, coagulation factors and blood pressure are concerned. Therefore oral micronized progesterone appears suitable for hormonal replacement therapy in various areas, essentially postmenopause therapy, premenstrual syndrome, correction of irregular cycles and pregnancy maintenance."
Climacteric. 2013 Aug;16 Suppl 1:69-78. "it appears that transdermal estradiol alone or combined with natural progesterone does not increase thrombotic risk."
PLoS One. 2014 Jan 21;9(1):e84698. doi: 10.1371/journal.pone.0084698. eCollection 2014.
Progesterone therapy, endothelial function and cardiovascular risk factors: a 3-month randomized, placebo-controlled trial in healthy early postmenopausal women."Results indicate that progesterone has short-term cardiovascular safety. Endothelial function, weight, bloodpressure, waist circumference, inflammation and
coagulation were unchanged"
CERTAIN other progestins CAN increase risk of DVT, those in birth control pills or medroxyprogesterone acetate. It is important to differentiate between different forms. :)
I only mention those 3 studies but I can send you more links privately.
Bio-identical estradiol taken non-orally has been shown by several studies to be quite safe in terms of DVT and even be protective. I have the studies if you want, as well.
QuotePlease don't use disinformation to hand-wave my 'hysteria' away.
I never said you were hysteric, just anxious. We all experience anxiety, including me and there is nothing wrong with that. I didn't mean to offend you. Sorry. :( I was also only speculating. Best to see your doctor about it.
Not disinformation, my assertions are based on several studies, science, not hearsay. I take a high dose of oral Prometrium (and non-oral estradiol) and my coagulation factors are normal, unchanged. :)
Hey KayXO, I have a question! :)
Like fall of 2014 I was switched over to the generic version of prometrium, which is manufactured by Teva. Is it still considered bio idenitical if its generic. I'm assuming yes right? Only reason I ask is cause I was looking up online and women were reporting bad side effects in general. Apparently it has something to do with how it's made (different fillers)
What's your take on that?
Teva is not much different, I think, in terms of inactives. You need to compare. I know the Prometrium I now take no longer contains peanut oil but sunflower oil. Some ppl are allergic to peanuts. Do you feel different on it? Effects still the same?
The only difference I see is the oil used (peanut vs. sunflower), the iron oxide (E172) added in Teva and glycerin vs. glycerol which I think are the same.
Back to normal now that I'm off it. I'll just have to stick to a lower dose, but I'm sure it'll be enough. I was feeling and seeing a difference at the lower dose, and have been getting good and consistent breast growth. I'll talk to my endo about it all next month.
P is not necessarily for everyone. I find that often the doses are too low to really see a significant effect and really judge whether P is beneficial or not. P is VERY quickly metabolized by the body even when injected IM, where it lasts 24-36 hours.
Quote from: KayXo on January 12, 2016, 05:30:54 PM
Teva is not much different, I think, in terms of inactives. You need to compare. I know the Prometrium I now take no longer contains peanut oil but sunflower oil. Some ppl are allergic to peanuts. Do you feel different on it? Effects still the same?
effects are still the same, was just curious...I was kind of suspecting that it was causing my depression but I realized it was other things triggering it.
Quick little update, so I'm going into my 3rd cycle for this month and I noticed a definite change in my breast consistency. It seems like my breast got fuller and a bit heavier compared to what it was pre-progesterone.
I wish I could post my pic here. However, the significant change that I noticed was with the upper part of the breast which accumulated some fat and made the slope a lot more breast like than before. I'm also happy to say that rear rounded out more and it's a bit of struggle wearing my skinny jeans lately lol Anyways, I am currently a 34 B/36 A girl and I cannot wait to report more changes in the next few weeks.
Hope y'all are having a great weekend. Be blessed xo
These are the changes that one would expect from adding progesterone. :)
Quote from: April_TO on January 24, 2016, 06:34:06 PM
Quick little update, so I'm going into my 3rd cycle for this month and I noticed a definite change in my breast consistency. It seems like my breast got fuller and a bit heavier compared to what it was pre-progesterone.
I wish I could post my pic here. However, the significant change that I noticed was with the upper part of the breast which accumulated some fat and made the slope a lot more breast like than before. I'm also happy to say that rear rounded out more and it's a bit of struggle wearing my skinny jeans lately lol Anyways, I am currently a 34 B/36 A girl and I cannot wait to report more changes in the next few weeks.
Hope y'all are having a great weekend. Be blessed xo
Yes I notice the same thing, especially with jeans now. It's a struggle lol.
So I am officially off on Spironolactone and switching to Cyproterone Acetate which could lead to dropping prometrium all together. So we shall see xo
Prometrium and cyproterone acetate are both progestogens BUT their potencies differ, so are their effects on the body. You may still benefit from bio-identical progesterone in other ways (mental benefit, sebum production, anti-diuretic, etc.). The progestogens can also increase the total progestogenic effect which may or may not be good.
Beware with cyproterone...it may cause depression/anxiety, lethargy, completely kill libido. It may cause prolactin to surge too much, leading to prolactinoma, a benign pituitary tumor. It can increase weight around belly and overall weight. It can also affect clotting and insulin sensitivity. Some complain from hot flashes which means that low T due to cyproterone is not compensated enough by E. I assume your doctor knows all this but just in case... :)
My endo told me that they dont prescribe it there, I don't know if I should change endo or try to speak to her again, what should I tell her? I really want to add prometrium to my hrt regimen
Quote from: Melanie ♡ on February 10, 2016, 12:18:37 AM
My endo told me that they dont prescribe it there, I don't know if I should change endo or try to speak to her again, what should I tell her? I really want to add prometrium to my hrt regimen
LOL. Here we go again...you can ask her why they don't prescribe it. Then we can go from there. I have a whole document on progesterone that you can show your doctor, with studies, benefits and "risks", etc. Please PM me.
Hi;
My doctor has just added Prometrium to my HRT medication (so now I am on E and P only) Oestrogen at 10am and Oestrogen and Prometrium at night time 10pm. I am just coming to the end of my first month on Promethium . My doctor & Pharmacist proposed that I should have it for 3 months continuously then move to a 20/10 day cycle to mimc the cis female hormonally cycle. I did query this but I was told by my pharmacist that the aim is to get the progesterone built up in one's system and get the body used to accepting it and also the combination of E&P will have an overall effect of dramatically lowering amy residual Testosterone and getting ones body to expect only female hormones on a regular basis.
Since commencing the Prometrium, I have noticed that my breasts have got fuller and a bit heavier compared to what it was pre-progesterone with upper part (pole) of each breast more rounded and gives the appearance that it has accumulated some fat and made the slope a lot more breast like in appearance rather than the pointed traffic cones I had before better than before. Also may areolae seem to have got more pinky and wider than they were at the beginning of the month (more noticeable as women's nipples). My nipples themselves have been very permanently erect since starting on my double dosage of Oestrogen a year ago. I have also noticed that my buttocks have rounded out more and it's a bit of struggle wearing my skinny jeans and women short shorts. But I am starting to notice more of a waist appearing, but I have also added lower belly fat, but interestingly I haven't gained weight. Also I am sleeping very soundly each night and somehow my skin feels incredibly super soft especially my face, buttocks, breasts and thighs.
I am looking forward to see what my results will be by the end of my first three months on the combined dosages.
Judith