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Community Conversation => Transitioning => Hormone replacement therapy => Topic started by: Richenda on March 30, 2016, 09:17:50 PM

Title: Dutasteride dizziness warning
Post by: Richenda on March 30, 2016, 09:17:50 PM
Hi folks,

Some of you may have seen me refer to a wobbly period with my HRT.

What I didn't mention was that this was physiological not merely a 'wtf' emotional moment.

5 weeks ago, despite being monitored by my GP and GIC I thought it would be a bright idea to switch from Finasteride to Dutasteride. I didn't think it would be that big an issue. After all it's just another T to DHT blocker, right? And to be fair to me, I ran out of F.

Well a week after starting the Dutasteride I started getting light-headed spells. I tried eliminating a load of other possibilities and I'm now pretty convinced it's Dutasteride. Today I googled 'dizzy' and 'Dutasteride' and discovered that this is a very common side effect that Glaxo Smith Kline hardly mention. Now admittedly, I have a susceptibility to dizziness with some meds e.g. minocyclin spins me out but I thought I should warn people. GSK may not like me mentioning this to you but it must be done for health and safety. Some of my light-headedness has been quite nasty. It's probably exacerbated by living in a very hot climate, the hottest city in the world, but be careful folks.

Now I have to wait a very long time to get it out my system. It has a huge half-life of up a month.

x
Title: Re: Dutasteride dizziness warning
Post by: KayXo on March 31, 2016, 12:28:53 PM
Dutasteride (similar to finasteride) also reduces concentrations of neurosteroids important for mood, learning and memory, such as tetrahydroxydeoxycorticosterone and allopregnanolone. This is why in some people (including women), depression/anxiety is noted, even after discontinuation, with finasteride. Had I known this years ago, I would never have taken either drug.

Please see https://www.susans.org/forums/index.php/topic,206700.0.html