Susan's Place Transgender Resources

Community Conversation => Transitioning => Hormone replacement therapy => Topic started by: NataliaDoll on April 10, 2016, 02:15:31 PM

Title: Hormone levels throughout day on hrt
Post by: NataliaDoll on April 10, 2016, 02:15:31 PM
So I take hrt I and I was wondering if anyone knows if your hormone levels may change throughout the day or if the women's range hormone levels will wear off after taking the pill as the day goes on or does it stay in the women's range? I take 1 spiro and 1 estrodial in morning and 1 estrodial in after noon. I always wonder is my hormone levels are the same by the time I go to sleep? I wonder how long it takes to get back into the male hormone range if you didn't take hormones.
Title: Re: Hormone levels throughout day on hrt
Post by: Laura_7 on April 10, 2016, 02:21:29 PM
Here is a graph showing that it really matters:
https://www.susans.org/forums/index.php/topic,186946.msg1665088.html#msg1665088

With sublingual intake levels rise fast, and drop after a few hours...
Sublingual intake bypasses the liver and thus causes less clotting factors and less strain on the liver.
So spreading the daily dose in a few small doses might be a good idea.
Otherwise there might be a menopausal like effect a few times a day which might affect mood.
The same is true for swallowing pills if times of intake are far away from each other, like once a day.

For sublingual intake micronized bioidentical estrogen like estrace or generics are  ideal.

Some poeple are sensitive some people do not feel much of an effect on mood.
In case of sensitivity there are small dose pills available, or pills might be broken in half.

You might talk all of this through with your doc.


*hugs*
Title: Re: Hormone levels throughout day on hrt
Post by: KayXo on April 10, 2016, 03:37:32 PM
Levels will fluctuate daily, more so in some, more so with certain routes of administration. It depends.

Womens' range is VERY wide, from 20 pg/ml to up to 75,000 so chances are, you're in the range at all times, even mens' overlaps that of women (10-40). The important thing is how you feel and overall feminization.