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Community Conversation => Transsexual talk => Male to female transsexual talk (MTF) => Topic started by: michelleh on September 24, 2016, 10:44:48 PM

Title: I am going to Try Finasteride and Hopefully Progesterone Any Thoughts?
Post by: michelleh on September 24, 2016, 10:44:48 PM
I have ask my Doctor to let me try Progesterone and Finasteride for breast growth and hair thicking. I heard Progesterone causes weight gain. Is the gains from Progesterone permanent? I read blogs where ladies cycle Progesterone in two week cycles and some half dose it. It seems it kinda like it is all an experiment how it goes and feels. I heard Progesterones causes masculine impact on the face any thoughts? It doesn't matter I still try it out!❤️❤️❤️❤️💋😘
Michelle
Title: Re: I am going to Try Finasteride and Hopefully Progesterone Any Thoughts?
Post by: ezjuliani on September 24, 2016, 10:57:54 PM
You want to gain weight.  It's so costly here in my country. Girls, my face needs serious work done on it nothing works no matter what I take.
O+bg

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Title: Re: I am going to Try Finasteride and Hopefully Progesterone Any Thoughts?
Post by: Dani on September 25, 2016, 06:44:23 AM
Do not forget the estradiol. I take mine under the tongue.
Title: Re: I am going to Try Finasteride and Hopefully Progesterone Any Thoughts?
Post by: HappyMoni on September 25, 2016, 07:40:57 AM
Hi Michelle,
   I really stalled out on breast growth at about 7 months or so. After surgery and stopping hormones for 6 weeks. I started back and saw a little growth. I started P less than 1 month ago and saw quite a bit of change in the breasts. It also made me a bit bitchy for  while. (a week) Nothing else noticed so far.
Monica
Title: Re: I am going to Try Finasteride and Hopefully Progesterone Any Thoughts?
Post by: michelleh on September 25, 2016, 08:29:36 AM
Thank You Monica!!!❤️
Michelle
Title: Re: I am going to Try Finasteride and Hopefully Progesterone Any Thoughts?
Post by: Rachel on September 25, 2016, 10:39:31 AM
Progesterone metabolizes to testosterone. My T is very low ( less then 3 ng/dl) so it is welcome.  If you do not have any breast tissue you may be disappointed in the result.

Finasteride caused me some gonad pain (minor) and loss of libido ( small amount). I was on it prior to being monitored by a doctor and after. I stopped finasteride a little while ago. It has side effects and I did not want to compound an issue ( suicidal ideation and attempts). Around the same time I came out and expressed full time. My suicidal ideation is a small fraction of what it was and I have and no further attempts. So most likely the change was from coming out and being me.  I need implants and will get them in the spring. Finasteride is a weak anti androgen.

What changed my life was estrogen and spironolactone at transitioning doses.

Talk to your doctor, make sure the doctor is competent in cross hormone therapy. Good luck,

Rachel

Title: Re: I am going to Try Finasteride and Hopefully Progesterone Any Thoughts?
Post by: kaitylynn on September 25, 2016, 10:40:31 AM
I am once again considering progesterone again in my regimen.  It was part of my HRT in the 90's and it was a bad experience for me...but then it was NOT what is prescribed today!  My endo has not been on board with the thought of my use of it, so I am holding off.  I think at year 2, I will use it again.  I have been blessed with some good development up top and my two sisters that use it are certain it will finish out the shape, but I am not in a huge hurry now.

Has your endo told you the brand of progesterone you will be using?
Title: Re: I am going to Try Finasteride and Hopefully Progesterone Any Thoughts?
Post by: Roxy on September 25, 2016, 10:49:17 AM
Progesterone is heavy unrated for trans women. It has a number of medical benefits aside from increased breast development.

However the only safe and effective form of progesterone is bioindentical progesterone.  Only ever use the bioindentical version.

I personally had good benefits from it. Multiple chest photos banned on facebook even with nipples not visible.
I now lose things down my top which I can't seem to quickly find. At the end of the night when I undress for bed , I am always suprised at what falls out of my bra eg money, phone, bank card , snacks etc
And I now have a guy that I never slept with cook for me everyday for the last 3 weeks.
My boobs are like some type of new superpower
Title: Re: I am going to Try Finasteride and Hopefully Progesterone Any Thoughts?
Post by: michelleh on September 25, 2016, 02:41:44 PM
Katherine,

I will be using progesterone (Prometrium) when the Doctor gets the blood test results back. I discussed the bioidentical aspect. We will see soon how it works.

❤️Michelle
Title: Re: I am going to Try Finasteride and Hopefully Progesterone Any Thoughts?
Post by: alex82 on September 25, 2016, 02:51:06 PM
Quote from: michelleh on September 25, 2016, 02:41:44 PM
Katherine,

I will be using progesterone (Prometrium) when the Doctor gets the blood test results back. I discussed the bioidentical aspect. We will see soon how it works.

❤️Michelle

Well, good luck. Maybe this time next year, you too will be finding Mars bars down there as you hunt for your house keys  :D

I think finasteride is ok. But is it a diuretic, or is that just me? Pretty sick of that side effect. I don't know why I take it - if anything my problem is that my hair is too thick, so within a fortnight of a cut, it's out of control again. Costs me a fortune to constantly have it thinned out and restyled, and the roots redone from fast growing.
Title: Re: I am going to Try Finasteride and Hopefully Progesterone Any Thoughts?
Post by: michelleh on September 25, 2016, 08:01:36 PM
Alex82,

I hope my hair becomes super thick on finasteride.👍🏻If my girls get big I would love it they are entirely too small for my frame right now anyways.🙃❤️

Michelle
Title: Re: I am going to Try Finasteride and Hopefully Progesterone Any Thoughts?
Post by: alex82 on September 26, 2016, 01:19:08 PM
Quote from: michelleh on September 25, 2016, 08:01:36 PM
Alex82,

I hope my hair becomes super thick on finasteride.👍🏻If my girls get big I would love it they are entirely too small for my frame right now anyways.🙃❤️

Michelle

If that's you, your hair looks good enough. I wouldn't think anything was amiss if I saw you in the street.

Beware the peeing. It sounds petty, but I'd really weigh up if it's worth going to the loo every twenty minutes for thicker hair. Now I'm on it, I'm scared that if I stop, it'll fall out.
Title: Re: I am going to Try Finasteride and Hopefully Progesterone Any Thoughts?
Post by: R R H on September 26, 2016, 02:19:49 PM
Quote from: michelleh on September 25, 2016, 08:01:36 PM
Alex82,

I hope my hair becomes super thick on finasteride.👍🏻If my girls get big I would love it they are entirely too small for my frame right now anyways.🙃❤️

Michelle

I spent 2 years on finasteride before my orchiectomy. It definitely thickened my hair and it contributed to other feminising effects. Breasts grew in conjunction with estrogen.

Looking back on it I also realise it had negative effects on me: some depression and elevated heart rate. It also caused some loss of libido.

As AA's go it's relatively weak but perhaps people focus too much on T rather DHT. It's DHT which finasteride hits.
Title: Re: I am going to Try Finasteride and Hopefully Progesterone Any Thoughts?
Post by: Sydney_NYC on September 26, 2016, 04:45:57 PM
After 2½ years on estrogen, spiro and Finasteride, my doctor just added progesterone to my HRT regimen. Even though I've developed to a good B cup, The roundness isn't there and my nipples are in a in-between stage. The look great in a bra, but naked I'm not happy with the shape. I asked her about progesterone during my 6 month checkup last week and she said that although they (Callen-Lorde) doesn't have it as part of the normal HRT, that she does prescribed on occasion and she thinks I could benefit from it. Even though it's only been 5 days since I started taking it, my breasts do feel a little bigger in the same bra compared to last week and I've been getting more of the growth pains I experienced at the start of HRT, so something is changing for sure. She said I should know within 1-3 months how effective progesterone is for me. I see her again in 3 months (instead of the normal 6) to make sure my body is behaving well with the progesterone.
Title: Re: I am going to Try Finasteride and Hopefully Progesterone Any Thoughts?
Post by: Aethersong on September 27, 2016, 01:57:12 PM
I've been on Finasteride since 6 months before starting HRT.  I'll remained on it as long as there is testosterone readily available, all be it now substantially blocked, that could be converted to DHT.

I've experienced a nice filling out of my hair, but regardless my hairs pretty thin/whispy so it'll never get thick or have a ton of body.  I don't really have any apparent balding spots anymore and that's all I ever wanted so it did the trick for me.  Nor have I had any of the negative side effects though that depends on individual.

I can't speak on the topic of Progesterone but it has also been something I've been curious about and if it's worth adding to my regular HRT regimen.  The responses I've read to this inquiry are usually pretty anecdotal so I don't know what to think.
Title: Re: I am going to Try Finasteride and Hopefully Progesterone Any Thoughts?
Post by: michelleh on September 27, 2016, 02:45:10 PM
Aethersong,

If your doctor knows their hormones why not? Worse case is it does 't work. What I read if it does work you will really like the results really!!! 😎

I am already seeing impact of the Finasteride my hair doesn't fall out at all.😊


Michelle
Title: Re: I am going to Try Finasteride and Hopefully Progesterone Any Thoughts?
Post by: galaxy on September 28, 2016, 06:41:10 PM
Finasteride doesnt work.
Title: Re: I am going to Try Finasteride and Hopefully Progesterone Any Thoughts?
Post by: Maybebaby56 on September 30, 2016, 08:14:28 AM
Quote from: michelleh on September 25, 2016, 08:01:36 PM
Alex82,

I hope my hair becomes super thick on finasteride.👍🏻If my girls get big I would love it they are entirely too small for my frame right now anyways.🙃❤️

Michelle

Hi Michelle,

I was on high-dose finasteride for a year or so, and while I did see some vellus hair start growing along my hairline where there was nothing before, the results were hardly spectacular. I'd say the longest hair I had was less than an inch (~ 2 cm), and it all got shaved off a couple of weeks ago when I had my hairline advance/brow lift as part of FFS. I don't think I am going to start talking finasteride again.  My T levels are less than a tenth of what they were pre-HRT, (which were low to begin with) and that alone will should help decrease DHT levels significantly.

You should also be aware that finasteride blocks 5-alpha-reductase Type II everywhere, including in your brain, not just at hair follicles. This can be a concern because it means pregnenolone cannot be converted to allopregnenolone, an important neurohormone. The results can be manifest, from suicidal tendencies, to loss of libido.  I myself developed chronic insomnia.

As far as progesterone, it may be worth a try, even though there is still no objective clinical evidence that it enhances breast growth. Still, there are many anecdotal accounts from transgirls on this site who will tell you they got results. 

However be aware that progestins down-regulate the expression of estrogen receptors throughout the body through genomic actions. The primary purpose of progesterone is to function as an anti-estrogen, inhibiting estrogen-induced proliferation of the endometrial lining of the uterus and maintain the uterus for pregnancy. Progesterone and other  progestins may influence central nervous system function and psyche, inhibit gonadotropin release, increase body temperature and appetite, and antagonize various central effects of estrogens. Progestins may also impair glucose tolerance and cause a slight hyperinsulinemia.

I guess this is all a long-winded reminder that you can't pick-and-choose hormone actions. Sex hormones regulate just about every metabolic function in the body.

If you and your endocrinologist are on the same page with this, try it and see how you feel.  You may get positive results, and you may not.

With kindness,

Terri
Title: Re: I am going to Try Finasteride and Hopefully Progesterone Any Thoughts?
Post by: Dani on October 06, 2016, 04:09:50 AM
Quote from: galaxy on September 28, 2016, 06:41:10 PM
Finasteride doesnt work.

It depends on why you are taking it.

Finasteride is very effective in blocking the conversion of Testosterone into DHT.
Title: Re: I am going to Try Finasteride and Hopefully Progesterone Any Thoughts?
Post by: Miss Clara on October 06, 2016, 11:04:00 AM
Finasteride works to reduce DHT levels that cause male pattern baldness.  I took it pre-GRS, as well as Dutasteride which is more effective than Finasteride.  I have no idea if it stopped hair loss, but I assume it helped.

My doctor didn't recommend me taking progesterone.  It's a pregnancy hormone to prepare the uterus and the milk glands in the breasts which is what causes the breasts to swell.  Afterward, the milk glands/ducts shrink back to normal leaving the breasts with less firmness (sag). 

My plan was to stay on estradiol for 2 years, get as much natural, firm breast growth as possible, then have shaped silicone implants inserted to give me the breast size and shape I've always wanted.  The new 5th generation (gummy bear) implants will maintain the shape of your breasts long term with reduced risk of rupture and capsular contracture so common with traditional round, smooth saline or silicone implants. 

I know that implants are not for everyone.  There are health risks, and a financial impact which can be hard to manage given that few insurance plans reimburse the cost of cosmetic surgery.  However, I've read that something like 60% of trans women eventually opt for breast augmentation.  That possibility should be a consideration in assessing the long term consequences of one's choices, like one's HRT regimen.  It's always best to have a complete picture of the benefits and risks ahead of any decision involving your body.
Title: Re: I am going to Try Finasteride and Hopefully Progesterone Any Thoughts?
Post by: KayXo on November 04, 2016, 08:23:13 PM
Quote from: Maybebaby56 on September 30, 2016, 08:14:28 AMYou should also be aware that finasteride blocks 5-alpha-reductase Type II everywhere, including in your brain, not just at hair follicles. This can be a concern because it means pregnenolone cannot be converted to allopregnenolone, an important neurohormone.

Correction: progesterone converts to allopregnanolone, a neurosteroid which has anti-depressant and anxiolytic effects, indirectly by converting to dihydroprogesterone thanks to 5 alpha reductase activity which is inhibited by finasteride so that you can potentially become anxious and depressed. At low doses of finasteride, some women have reported no effect on the brain while still reaping benefits for scalp hair.

QuoteAs far as progesterone, it may be worth a try, even though there is still no objective clinical evidence that it enhances breast growth.

It promotes lobulo-alveolar growth. There is clinical unequivocal evidence for this.

QuoteHowever be aware that progestins down-regulate the expression of estrogen receptors throughout the body through genomic actions. The primary purpose of progesterone is to function as an anti-estrogen, inhibiting estrogen-induced proliferation of the endometrial lining of the uterus and maintain the uterus for pregnancy. Progesterone and other  progestins may influence central nervous system function and psyche, inhibit gonadotropin release, increase body temperature and appetite, and antagonize various central effects of estrogens. Progestins may also impair glucose tolerance and cause a slight hyperinsulinemia.

It is important to differentiate between progesterone and other progestogens as their effects can differ quite significantly.

Quote from: Clara Kay on October 06, 2016, 11:04:00 AMMy doctor didn't recommend me taking progesterone.  It's a pregnancy hormone to prepare the uterus and the milk glands in the breasts which is what causes the breasts to swell.  Afterward, the milk glands/ducts shrink back to normal leaving the breasts with less firmness (sag).

They only shrink back (partially) if you stop progesterone. Same if you stop taking estradiol. Why would you stop taking either?

Title: Re: I am going to Try Finasteride and Hopefully Progesterone Any Thoughts?
Post by: Harley Quinn on November 05, 2016, 01:21:08 PM
Quote from: KayXo on November 04, 2016, 08:23:13 PM
Correction: progesterone converts to allopregnanolone, a neurosteroid which has anti-depressant and anxiolytic effects, indirectly by converting to dihydroprogesterone thanks to 5 alpha reductase activity which is inhibited by finasteride so that you can potentially become anxious and depressed. At low doses of finasteride, some women have reported no effect on the brain while still reaping benefits for scalp hair.

It promotes lobulo-alveolar growth. There is clinical unequivocal evidence for this.

It is important to differentiate between progesterone and other progestogens as their effects can differ quite significantly.

They only shrink back (partially) if you stop progesterone. Same if you stop taking estradiol. Why would you stop taking either?
So I take it as you're an advocate of Progesterone?
Title: Re: I am going to Try Finasteride and Hopefully Progesterone Any Thoughts?
Post by: KayXo on November 06, 2016, 08:22:02 AM
I think it can have its place in a transsexual woman's regimen based on findings from studies (and anecdotal evidence) but in some women, it can apparently have a negative effect on mood, lead to too much weight gain and even cause some breast shrinkage due to its anti-estrogenic effect. Trial and error.
Title: Re: I am going to Try Finasteride and Hopefully Progesterone Any Thoughts?
Post by: Lady_Oracle on November 06, 2016, 09:34:00 AM
I never understood that argument against starting P (because its a pregnancy hormone) thats not all it is. Its thanks to P that cis women reach the later stages of breast development. When ovulation and menstruation begin, progesterone is introduced and so the breasts go into a new growth phase.

I've been on it for years and yes I'm still small cupped (cause genetics) however they're way more mature than I've seen from most trans women, nipple and areola size wise and there was a couple of times I had been off P for months and didn't notice a change in size. I think all trans women should try it vs never trying it at all.
Title: Re: I am going to Try Finasteride and Hopefully Progesterone Any Thoughts?
Post by: Ange on November 07, 2016, 03:19:48 AM
Since I intend to breastfeed on a far away future, and my breast are actually A-- (cute but barely visible), shoudl I start Progesterone ?

I really need to gain weigth BTW. (I'm 58 kg for 1m80)
Title: Re: I am going to Try Finasteride and Hopefully Progesterone Any Thoughts?
Post by: Lady_Oracle on November 07, 2016, 06:32:05 AM
Progesterone is crucial in developing milk ducts so yep you need to be on P and it should help you gain weight too.
Title: Re: I am going to Try Finasteride and Hopefully Progesterone Any Thoughts?
Post by: Ange on November 07, 2016, 07:56:15 AM
I've only been 18 monthes on HRT (even less in fact since I had SRS), so I wonder if this is enough.

I've read that progesterone slow down breast development, and that it would be better used after a few years on oestrogens.

I'd like to begin asap but maybe I should wait another 6 monthes or even 1 or 2 years.
Title: Re: I am going to Try Finasteride and Hopefully Progesterone Any Thoughts?
Post by: Lady_Oracle on November 07, 2016, 08:37:12 AM
If that were true then I wouldn't have developed as nearly as well as I did and would still be at like tanner stage 3. I began the process of inducing earlier this year. If you're interested shoot me a pm and I'll send you some info.

side note: I started progesterone from day 1 of hrt and everything worked out fine.
Title: Re: I am going to Try Finasteride and Hopefully Progesterone Any Thoughts?
Post by: KayXo on November 07, 2016, 09:18:04 AM
Quote from: Lady_Oracle on November 07, 2016, 06:32:05 AM
Progesterone is crucial in developing milk ducts

Not milk ducts but milk glands (lobules and acini/alveoli), hence lobulo-alveolar growth. Milk ducts are especially stimulated by estrogen.
Title: Re: I am going to Try Finasteride and Hopefully Progesterone Any Thoughts?
Post by: Lady_Oracle on November 07, 2016, 12:38:00 PM
Thanks Kay! I get my terms mixed up, I had a feeling it wasn't right. 

I'd also like to say I had success with inducing about 3 months after I started, actual milk coming through but it wasn't a lot, at least not yet. I might make a thread about it. Its good to know my breasts at the very least are responsive.
Title: Re: I am going to Try Finasteride and Hopefully Progesterone Any Thoughts?
Post by: KayXo on November 07, 2016, 02:35:05 PM
Progesterone actually strongly inhibits milk letdown and lactation but it's thanks to that hormone that milk glands form in the first place.
Title: Re: I am going to Try Finasteride and Hopefully Progesterone Any Thoughts?
Post by: Maybebaby56 on November 07, 2016, 04:57:58 PM
Quote from: KayXo on November 04, 2016, 08:23:13 PM
Correction: progesterone converts to allopregnanolone

That was my mistake.  Thank you for catching that.

Quote from: KayXo on November 04, 2016, 08:23:13 PM
It promotes lobulo-alveolar growth. There is clinical unequivocal evidence for this.

Unless you are lactating, the milk glands are small fraction of total breast size, are they not?

Quote from: KayXo on November 04, 2016, 08:23:13 PM
It is important to differentiate between progesterone and other progestogens as their effects can differ quite significantly.

The effects I mentioned apply to progesterone.

~Terri
Title: Re: I am going to Try Finasteride and Hopefully Progesterone Any Thoughts?
Post by: Lady_Oracle on November 07, 2016, 08:50:39 PM
Quote from: KayXo on November 07, 2016, 02:35:05 PM
Progesterone actually strongly inhibits milk letdown and lactation but it's thanks to that hormone that milk glands form in the first place.

Yep! Once I noticed clear/cloudy fluid coming out I stopped taking P and milk started coming in. It took about a week or so and then I started getting sprays. I basically followed the same protocols most who induce try and had success. I didn't think it'd be possible pre-op still but I managed.
Title: Re: I am going to Try Finasteride and Hopefully Progesterone Any Thoughts?
Post by: Ange on November 08, 2016, 09:38:42 AM
Quote from: Maybebaby56 on November 07, 2016, 04:57:58 PM
Unless you are lactating, the milk glands are small fraction of total breast size, are they not?

Mmm, since my breast size is barely existant, I think it would change much in my case :D
Title: Re: I am going to Try Finasteride and Hopefully Progesterone Any Thoughts?
Post by: KayXo on November 08, 2016, 09:48:40 AM
Quote from: Maybebaby56 on November 07, 2016, 04:57:58 PMUnless you are lactating, the milk glands are small fraction of total breast size, are they not?

No. I see for myself how progesterone makes my breasts wider and fuller thanks to stimulating the formation of glands. There is a significant difference.