Hello everyone!:)
First of all, please excuse my English. I had an appointment with my endocrinologist on Wednesday and we discussed my blood work results. I have been on hormones for 2 months and 2 weeks and my E levels were 297.8 pmol/l (81 pg/mL). I wanted to ask if these levels are normal for someone who has been on hormones for 2 months and two weeks? Thank you so so much for those who will answer! <3
Victoria
Welcome to Susan's Place. Normally the transition targets the range of 100-200 pg/ml however estradiol doesn't last long in the body. If you were 24 hour between your last dose and your blood test, your levels for much of that time would be a good deal higher depending on exactly how your pills were taken. My estradiol levels tend to run at about 50 pg/ml and I am seeing development even though that would be considered a menopause level. Hormones take months to produce results and some people take longer than others. Normally you would see noticeable development after about 6 months to a year. I am including a table you might find interesting.
ESTRADIOL LEVELS
SEX pg/ml
Women (> 18 years old)
Follicular Phase 30-120
Ovulatory Peak 130-370
Luteal Phase 70-250
Post-Menopausal 15-60
Male 15-60
TOTAL TESTOSTERONE LEVELS
SEX ng/dl ng/ml
Females 6 - 86 0.1 - 1.2
Males 270 - 1100 2.4 - 12
Conversion factor: 1 ng/ml = 3.47 nmol/lWe issue to all new members the following links so you will best be able to use the web site.
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After 60 days my E levels were slightly lower than yours when I tested 4 hours after my last dose. Now they are above 100 pg/ml if I test 12 hours after my last dose and close to 200 if I test 6 hours after my last dose. I'm dosing twice a day so the level is staying between 100 to 200 all the time. So your E levels will probably continue to rise given time.
Conform and be dull. —James Frank Dobie, The Voice of the Coyote
E levels rise and fall within 24 hours so they really don't mean much. What is more important is how you feel, breast growth, body hair, fat distribution, facial changes, etc. I noticed my breasts growing within a couple of months of starting HRT and lots of pain. Increased fat in the thighs and buttocks within 2-4 months, body hair growing slower within days. You should see at least some change at 2 months, IMHO.
Thanks girls! You calmed me down about my E levels. The blood test was made after 12 hours of my last dose.
Another question I have is about my T levels. I'm currently taking Biculatamide as anti-androgen. I have noticed a dramatic decrease in my body hair BUT I experience no changes in my face whatsoever. Also, I have only little to no pain in my breasts. My T levels are extremely high (30.88 nmol/l and my doctor said genetic male T levels range from 8.64 - 29.0 nmol/l). I'm so confused and depressed about my T levels. I have read that Biculatamide increases your T levels drastically but it runs free in your blood and is not used by your body but I'm still not happy about having hight T levels knowing that I see no face changes or development in breasts. I'm thinking about switching to Spiro. What do you suggest?
I am using spiro and it dropped my T from a pretty high level to where it is now undetectable. Some people have reported bad side effects with spiro but I have felt good on it. It did take a while to adjust but I'm not suffering any ill effects at all. You just need to experiment with salt and water intake to find a level that keeps you feeling good.
Conform and be dull. —James Frank Dobie, The Voice of the Coyote
Quote from: Moon_18 on April 01, 2017, 03:59:46 AM
Another question I have is about my T levels. I'm currently taking Biculatamide as anti-androgen. I have noticed a dramatic decrease in my body hair BUT I experience no changes in my face whatsoever. Also, I have only little to no pain in my breasts. My T levels are extremely high (30.88 nmol/l and my doctor said genetic male T levels range from 8.64 - 29.0 nmol/l). I'm so confused and depressed about my T levels. I have read that Biculatamide increases your T levels drastically but it runs free in your blood and is not used by your body but I'm still not happy about having hight T levels knowing that I see no face changes or development in breasts. I'm thinking about switching to Spiro. What do you suggest?
Bicalutamide ONLY blocks T so there is no sense in measuring levels. I suspect the reason you aren't seeing much change is too little E. Please discuss this with your doctor.
If Bicalutamide only blocks T receptors and not its production then does Spiro stop production of T? Because other girls are taking Spiro and their T levels drop.
Spiro stops the production of T.
Conform and be dull. —James Frank Dobie, The Voice of the Coyote
Thank you, Deborah! I made up my mind, I'm goint to ask my doctor to put me on Spiro. :)
Spiro doesn't stop production but reduces it. Additionally, it blocks T.
But if Spiro doesn't stop the production of T then why T levels in girls who take Spiro drop and it doesn't drop in girls who take Biculatamide?
It reduced my blood concentration of T from 826 ng/dl to less than 3 ng/dl. Perhaps that is technically not completely stopped but it is effectively stopped.
Conform and be dull. —James Frank Dobie, The Voice of the Coyote
Deborah, may I ask how much time it took for your T levels to drop to current levels? :)
It took a while. The T stubbornly resisted until we raised the dose pretty high.
Initially 826 ng/dl
60 days 158 ng/dl
8 months 120 ng/dl
Doubled spiro dose
14 months 19 ng/dl
20 months <3 ng/dl
It's remained there since.
Conform and be dull. —James Frank Dobie, The Voice of the Coyote