Susan's Place Transgender Resources

Community Conversation => Transitioning => Hormone replacement therapy => Topic started by: Robin_p on November 23, 2007, 04:49:09 PM

Title: Thinking of switching hormones.
Post by: Robin_p on November 23, 2007, 04:49:09 PM
Hi all!!!

I was wondering if anyone has switch from Premarin to Estradiol?

I have been on Premarin and Spiro Since July of this year. I love the effect i have been getting so far physically and mentally.

The only reason so far why i'm thinking about switching hormones is that Estradiol is $20 cheaper and comes in generic form. My insurance from work covers most of my prescriptions cost.

giggles, i dont really care that Premarin is mare urine. (I'm an alcoholic in recovery i drank much worse than that).
Title: Re: Thinking of switching hormones.
Post by: tinkerbell on November 23, 2007, 06:12:55 PM
Hi Robin (beautiful name :))

About five years ago, my insurance company stopped paying for Premarin so my endo had to switch me to Estradiol (generic Estrace).  My breasts started to hurt once again even though I had been on hormones for many years prior to Estrace; other than that, I didn't experience any other major changes whatsoever.

True, Estradiol is much cheaper than Premarin and it is not made hurting the poor horsies!  :)

tink :icon_chick:
Title: Re: Thinking of switching hormones.
Post by: Wing Walker on November 24, 2007, 01:17:54 AM
Hello, Robin,

I started my HRT on oral estradiol and it did well by me.  Some estradiol plus an androgen blocker like spironolactone and five years and I am grateful for my results.

There are many articles on the web concerning the safety of premarin in the human body. 

For insurance purposes, estradiol tabs work for me.

Wing Walker
Flying Sober
Title: Re: Thinking of switching hormones.
Post by: Tanya1 on November 24, 2007, 10:25:42 AM
Quote from: Wing Walker on November 24, 2007, 01:17:54 AM
.

There are many articles on the web concerning the safety of premarin in the human body. 

Wing Walker
Flying Sober

They are very hard on the liver, they have many chemicals which can't bind with receptors or be used by the body because it doesn't belong there!

Although many get results, bio hormones put much less strain to the bodies organs and they seem to be best suitable to the human body since it's naturaul! honestly I don't think plant hormones are naturaul because they are for PLANTS not humans!- 17b estrodial is they best  ;D

Title: Re: Thinking of switching hormones.
Post by: seldom on November 24, 2007, 06:02:04 PM
Quote from: Tanya1 on November 24, 2007, 10:25:42 AM
Quote from: Wing Walker on November 24, 2007, 01:17:54 AM
.

There are many articles on the web concerning the safety of premarin in the human body. 

Wing Walker
Flying Sober

They are very hard on the liver, they have many chemicals which can't bind with receptors or be used by the body because it doesn't belong there!

Although many get results, bio hormones put much less strain to the bodies organs and they seem to be best suitable to the human body since it's naturaul! honestly I don't think plant hormones are naturaul because they are for PLANTS not humans!- 17b estrodial is they best  ;D


17b Estradiol (Estrace) IS plant based.  It comes from SOY BEANS.  Its natural because the human body processes the plant based estrogens from Soy as close to bio-identical as possible.  Also when taken sub lingually it goes directly in the bloodstream bypassing the liver.    Its called natural because the amount of processing and how the body reacts to the hormone. 
Title: Re: Thinking of switching hormones.
Post by: Tanya1 on November 24, 2007, 11:11:20 PM
^ LOL wow, thanks for letting me know that! I really didn't know that though. so hold on a minute, how come regular soy like herbal hormones are ineffective while Estrofem is effective?
Title: Re: Thinking of switching hormones.
Post by: seldom on November 25, 2007, 12:50:32 AM
Because of the chemical process involved.  Estrace is still a pharmaceutical.  A chemist designed it.  Those herbals are ineffective because of the processing.  Estrace is basically optimized to use a specific chemical component of soy and ONLY that component that the human body recognizes as estrogen.  Okay, that is overly simplified explanation.  Its basically chemistry.  Its one specific molecular structure concentrated as supposed to an herb. 
Title: Re: Thinking of switching hormones.
Post by: Tanya1 on November 25, 2007, 09:38:19 AM
Quote from: Amy T. on November 25, 2007, 12:50:32 AM
Because of the chemical process involved.  Estrace is still a pharmaceutical.  A chemist designed it.  Those herbals are ineffective because of the processing.  Estrace is basically optimized to use a specific chemical component of soy and ONLY that component that the human body recognizes as estrogen.  Okay, that is overly simplified explanation.  Its basically chemistry.  Its one specific molecular structure concentrated as supposed to an herb. 


ohhh, I get it, so they take one molecular structure of soy that's identical to human E and the body regonizes it as no different, so it's metabolized and processed the same way as human E in genetic females.

that right?
Title: Re: Thinking of switching hormones.
Post by: kimmie on November 25, 2007, 05:18:23 PM
I started on permarin in 96 but they did nothing for me,and I give up.
In aug of 07 I started on delestrongen I M and I have a c cup now
hope this helps.
Title: Re: Thinking of switching hormones.
Post by: gothique11 on November 25, 2007, 11:09:17 PM
I was on horsepee for a 8-9 months. It did some things. However, it made my legs always feel achy. I didn't feel too good on it after those many months, so I switched to Estrace and I felt much better and I also started to notice a lot more changes . I've been on Estrace for 7-8 months. It seems to work for me, with no side effects, and I feel better over all. Plus, I swear I changed a lot on Estrace vs horse pee.
Title: Re: Thinking of switching hormones.
Post by: straycat on November 28, 2007, 09:05:38 AM
Quote from: Tanya1 on November 25, 2007, 09:38:19 AM
ohhh, I get it, so they take one molecular structure of soy that's identical to human E and the body regonizes it as no different, so it's metabolized and processed the same way as human E in genetic females.

that right?
Just to be clarify this, the identical estrogen is not already present in soy.  The plants contain compounds that are used as the raw material in synthesizing the identical molecule during a manufacturing process.
Title: Re: Thinking of switching hormones.
Post by: Robin_p on January 21, 2008, 02:10:00 PM
Thanks Everyone!!!! I will be seeing my endo in Janurary and will ask him to switch me.

Posted on: November 29, 2007, 10:00:20 PM
I switched Hormones to estadiol the pills. The first thing i notice is the price. I used to pay $30 for horse piss (giggles) Now i pay $6.71 for estadiol. That's awesome in my book.

Title: Re: Thinking of switching hormones.
Post by: gothique11 on January 22, 2008, 02:50:14 AM
I switched from horse pee to estrace, and I find estrace is better. The horse pee and me didn't get along for some reason -- I'd get strange cramps at night (like achy legs), I'd get hot flashes, and I'd get a weird feeling in my legs and arms. I don't know what it was about those pills, but they just didn't agree with me. With estrace, I've had no health problems and no weird feelings. I feel much better on them.