I'm a 25 year old intersex woman. Born with partial androgen insensitivity. My genitals were more male than female so i was raised male. I changed my gender when I was 16. Still have testicles. Started hormone treatment at 19. Treatment was almost the same as for a transgender woman. Estrogen(pills) and an antiandrogen(Androcur).
6 months ago I quit the anti androgen and use estrogen(patches) only since then. The testosterone kept being stable (between 0.7-1.3 nmol/l) in female range for 5 months, Estrogen levels became a little too high and my gynaecologist lowered the estrogen dose.
The estrogen got down to a lower and better level and is now 240pmol/l but after 2 months of the lower dose estrogen and 6 months without antiandrogen testosterone level is now 4.1 nmol/l. Normal range for female is 0,3-3.0 nmol/l as far as I know.
I'm wondering how it can be elevated like that when it was 1.3nmol/l last month after 5 months without antiandrogens. I thought after 5 years of anti androgens and 5 months of being stable without antiandrogen it wouldn't really change again.
Before I started hormone treatment my testosterone level was 12 nmol/l but because of my partial insensitivity to androgens I didn't get into male puberty. Because an orchidectomy isn't possible for now I still have my testicles.
Even though partial insensitivity to androgens Is there any possibility of defeminization and masculinization of the body with a testosterone level of 4.1 nmol/l? If not, at what testosterone level it possibly will?
Would it be better to wait another month and see if it stabilizes, or would it be best to up the dose of estrogen to block the testosterone better,
or taking an anti androgen again?(Which I don't prefer because of the possible long term side effects)
Hi Marina 🙋♀️ Welcome to Susan's Place! I'm Jessica. I won't try to answer your question, I'm still learning how to keep my levels stable.
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Marina1993, best to work with your drs as they are the ones who should know how to adjust your hormone input to get the result you need and want.
Marina, I wouldn't worry about it too much, but I would definitely talk to your doctor about it as wel las keep on eye on your T levels over time.
As you are partially insensitive to androgens, I'd think that a level slightly above female range wouldn't cause much problems. Also, your reduction in estrogen dose could account for the rise in T as estrogen lowers production of T.
I'm not an expert, however and you should discuss this with your doctor.
Quote from: KayXo on February 22, 2018, 12:08:56 PM
As you are partially insensitive to androgens, I'd think that a level slightly above female range wouldn't cause much problems. Also, your reduction in estrogen dose could account for the rise in T as estrogen lowers production of T.
I'm not an expert, however and you should discuss this with your doctor.
This would be my guess as well.