Susan's Place Transgender Resources

Community Conversation => Transitioning => Hormone replacement therapy => Topic started by: pamelatransuk on August 17, 2018, 07:19:47 AM

Title: Comparison of our HRT Blood Test Results after 6 or 7 Months
Post by: pamelatransuk on August 17, 2018, 07:19:47 AM
Hello Ladies

You may recall that in May I compiled a "Comparison" thread just like this one but for after 3 or 4 months and first of all I wish to copy the final table to this thread as below:

                               E (Intnl)            E (US)       T (Intnl)       T (US)

Pamela                       922                  251               1.6              46
Sarah                         297                    81               1.1              32
Devlyn                       338                    92                4.8            140
Deborah                     261                    71                5.5            158
Kathy                         698                  190                0.2                5.8
Tonya                         224                    61                5.4            156
Katie                          364                     99               0.2                5.8
Kaitylynn                    220                     60               3.8             110
Alison                       1178                   321                1.6              47
Charlie Nicki                173                    47                5.3             154
Sadie                        2577                   702               0.4               12   
KayXo                         974                   265               1.5               43
Casady                        821                  224                4.2             121

So once again I invite anyone that wishes to provide with their E and T Blood Test results after either 3/4 months or after 6/7 months, please do so on this thread please and I shall happily add you to the table(s). Please state whether you are providing International or US Units and I shall happily convert accordingly as the table provides both for comparison purposes.

I am doing this exercise in May, August and November 2018 and February 2019 just to see if there are any statistical trends we may see; I accept we may not see anything more than coincidence especially since I do not possess (and I do not wish to possess) details of dosage. Anyone may inform me but only if they wish of their medication name but not dosage of course. I do not wish any table to be regarded in any way as "League" or "Performance" table.

I am at present on Evorel Patches and Finasteride but that may change when I see my doctor Friday 24th. Obviously I have mixed feelings; I am delighted by my high E reading but disappointed with my T reading as it has increased. I wonder if I may be put on injections to reverse the increase in T?

I shall add KayXo's and Casady's readings in due course when I receive them and I shall add others' who choose to inform of their 3/4 and 6/7 month readings. So at present the table consists of 11 members:

                               E (Intnl)            E (US)       T (Intnl)       T (US)

Pamela                     1662                  453               2.4              69
Sarah                         349                    95               0.4              12
Devlyn                       720                   196               1.8              53
Deborah                     430                   117               4.2            120
Kathy                         303                     83              0.5               14
Tonya                         268                    73                1.1              32
Katie                          254                     69               0.2                5.8
Kaitylynn                    162                     44               1.0               30
Alison                         826                   225             <0.1             <2.5
Charlie Nicki                213                     58               2.6              74
Sadie                        1296                   353               0.4               12   

Thanking all participants and to general readers of this thread, I hope you find the figures of some value.

Anyone may of course comment on the table(s) and as previously requested provide their own readings.

Hugs to all

Pamela

Title: Re: Comparison of our HRT Blood Test Results after 6 or 7 Months
Post by: pamelatransuk on August 20, 2018, 03:34:46 AM
KayXo no longer possesses her E and T Blood test results after 6/7 months but she has very kindly provided me with the following information as I was astounded at my E reading of 1662 Intl 453 (US), which is helpful to me and probably to others on HRT.

Thank you KayXo and as you can see my I am on Evorel Patches and Finasteride dosages to be sent by PM.

Hugs

Pamela

QUOTE FROM KAYXO:

1,662 pmol/L is not too high, E2 levels fluctuate anyways. Is this estradiol or estrogen levels? Women have much, much higher levels, during pregnancy (and even during a menstrual cycle, up to 3,700), up to 275,000 pmol/L. It's safe, no worries. I have much higher levels than you.


E never converts to T, ever. Otherwise, it would not be given to men who have prostate cancer whose survival depends on sustaining very low levels of T to stop the progression of cancer. When my E2 was around 5,000-14,000 pmol/L, my T was 0.1-0.3 nmol/L.

<NO ->-bleeped-<- Links Please>
Admin
Title: Re: Comparison of our HRT Blood Test Results after 6 or 7 Months
Post by: fgsb on August 20, 2018, 12:34:41 PM
Age would be good to include in the table
Title: Re: Comparison of our HRT Blood Test Results after 6 or 7 Months
Post by: Allison S on August 20, 2018, 04:02:15 PM
I'm 28 now, I started hrt at 27 years and 3 months old.
Where do I stand on this chart as far as hrt effectiveness on levels?
The way the numbers are listed it's a bit confusing for me. Even knowing what my levels are I can't place which are mine and which are the people below/above me.

Sent from my VS501 using Tapatalk

Title: Re: Comparison of our HRT Blood Test Results after 6 or 7 Months
Post by: Cindy on August 20, 2018, 05:12:27 PM
Please be aware that

QUOTE FROM KAYXO:

1,662 pmol/L is not too high, E2 levels fluctuate anyways. Is this estradiol or estrogen levels? Women have much, much higher levels, during pregnancy (and even during a menstrual cycle, up to 3,700), up to 275,000 pmol/L. It's safe, no worries. I have much higher levels than you.

Is a personal opinion and not a medical opinion. I know on no endocrinologists that would be happy with a TG woman having E levels at those levels.
Title: Re: Comparison of our HRT Blood Test Results after 6 or 7 Months
Post by: Devlyn on August 20, 2018, 05:18:17 PM
Some peoples ideas of safe hormone levels make you wonder if they'd take motorcycle drivers education classes from Evel Knievel.  :laugh: :laugh: :laugh:

My doctor wants me in NORMAL female ranges, not the levels of an ovulating giraffe.  ;D

Quote from: fgsb on August 20, 2018, 12:34:41 PM
Age would be good to include in the table

I'm 56.
Title: Re: Comparison of our HRT Blood Test Results after 6 or 7 Months
Post by: pamelatransuk on August 21, 2018, 05:29:19 AM
fgsb

Thank you for your comment and I shall consider either age or age ranges on future tables and of course anyone wishing to provide their age may do so now by all means.


Allison

Thank you for your comments.

Forgive me if I have misled you but I am not trying to measure HRT effectiveness but merely trying to see if there is or will be trends over time - 3 months to 6 months to 9 months to 12 months. I suggest all we may look out for at this point is whether E Levels and/or T levels have improved or worsened or stayed virtually the same. My E has improved but is very high but my T has also increased hence worsened. Your E has decreased but again so have several others' E but your T has thankfully improved to the point of almost nil.

I shall leave a line between each person's results on the next table to ease reading; next table to be inserted as soon as others may provide their results.

Hoping this helps

Hugs to all

Pamela


Title: Re: Comparison of our HRT Blood Test Results after 6 or 7 Months
Post by: pamelatransuk on August 21, 2018, 05:36:02 AM
Quote from: Cindy on August 20, 2018, 05:12:27 PM
Please be aware that

QUOTE FROM KAYXO:

1,662 pmol/L is not too high, E2 levels fluctuate anyways. Is this estradiol or estrogen levels? Women have much, much higher levels, during pregnancy (and even during a menstrual cycle, up to 3,700), up to 275,000 pmol/L. It's safe, no worries. I have much higher levels than you.

Is a personal opinion and not a medical opinion. I know on no endocrinologists that would be happy with a TG woman having E levels at those levels.

Thank you Cindy. I am truly grateful for your advice. Obviously 3700 is too high for a transwoman. Please confirm you mean 1662 is also too high. I think it is too high but I wish to confirm you refer to that figure also please.

I think we should expect E levels up to 1000 (unless BT taken too early after dose which may be why mine is so high this time!).

Thanking you

Pamela
Title: Re: Comparison of our HRT Blood Test Results after 6 or 7 Months
Post by: pamelatransuk on August 22, 2018, 03:32:10 AM
I confirm that that my doctor also as expected considers my E reading of 1662 too high and has requested another BT which I shall arrange shortly and I shall inform you of the revised reading next week and produce a fresh table.

Pamela
Title: Re: Comparison of our HRT Blood Test Results after 6 or 7 Months
Post by: PurplePelican on August 22, 2018, 03:56:28 AM
Quote from: Cindy on August 20, 2018, 05:12:27 PM
Is a personal opinion and not a medical opinion. I know on no endocrinologists that would be happy with a TG woman having E levels at those levels.

I'll introduce you..
Title: Re: Comparison of our HRT Blood Test Results after 6 or 7 Months
Post by: Kirsteneklund7 on August 22, 2018, 04:17:52 AM
Hi Pamela,
                   I've had a blood test this week I will pass on the results to you this weekend. I think it will be about 600 nm/ L. Also while your level was running  at 1660 did you get addicted to soap operas and lose the ability to parallel park( ha ha).
With friendship, hugs, Kirsten.

Sent from my SM-G930F using Tapatalk
Title: Re: Comparison of our HRT Blood Test Results after 6 or 7 Months
Post by: pamelatransuk on August 25, 2018, 06:28:51 AM
Thank you Kirsten for sending me your first and second quarter results and therefore I have added you to the 3/4 Month Comparison Table as below and I have also left space between each person girl's results to ease reading.

I am still "theoretically" on 1662 (Intnl) for second quarter and I feel fine but of course it is likely inaccurate and next week I shall produce fresh 6/7 Month Comparison Table to include Kirsten's result and my revised presumably accurate result.

I confirm any other girls may still send me their first or second quarter results or both either Intnl or US and I shall happily convert for purposes of the tables.


                                   HRT Blood Test Results after 3 or 4 Months


                               E (Intnl)            E (US)       T (Intnl)       T (US)

Pamela                       922                  251               1.6              46

Sarah                         297                    81               1.1              32

Devlyn                       338                    92                4.8            140

Deborah                     261                    71                5.5            158

Kathy                         698                  190                0.2                5.8

Tonya                         224                    61                5.4            156

Katie                          364                     99               0.2                5.8

Kaitylynn                    220                     60               3.8             110

Allison                       1178                   321                1.6              47

Charlie Nicki                173                    47                5.3             154

Sadie                        2577                   702               0.4               12
   
KayXo                         974                   265               1.5               43

Casady                        821                  224                4.2             121

Kirsten                        915                   249               0.8               23


Thanking you and Hugs to all.

Pamela
Title: Re: Comparison of our HRT Blood Test Results after 6 or 7 Months
Post by: Kirsteneklund7 on August 25, 2018, 06:44:51 AM
It's a great idea for a post Pamela. Fantastic focal point for ongoing discussions.
Big hugs , Kirsten.


Sent from my SM-G930F using Tapatalk

Title: Re: Comparison of our HRT Blood Test Results after 6 or 7 Months
Post by: pamelatransuk on August 30, 2018, 08:22:03 AM
Hello again

When I started this thread I had just received my BT results and was surprised at the very high E reading of 1662 (Intnl) 453 (US) and disappointed that my T had increased. Consequently it was decided to do another BT for E only and to put me on Decapeptyl/Triptorelin injections for the increase in T. I had the BT for E this week and it has come down slightly but not as much as I expected to 1575 (Intnl) 429 (US).

I have also received Kirsten's BT results for the 6/7 Month Comparison and therefore I have produced the latest table below:


                                  HRT Blood Test Results after 6 or 7 Months


                               E (Intnl)            E (US)       T (Intnl)       T (US)

Pamela                     1575                  429               2.4              69

Sarah                         349                    95               0.4              12

Devlyn                       720                   196               1.8              53

Deborah                     430                   117               4.2            120

Kathy                         303                     83              0.5               14

Tonya                         268                    73                1.1              32

Katie                          254                     69               0.2                5.8

Kaitylynn                    162                     44               1.0               30

Allison                         826                   225             <0.1             <2.5

Charlie Nicki                213                     58               2.6              74

Sadie                        1296                   353               0.4               12

Kirsten                       422                    115               0.4               12 


Again I confirm any other girls may still send me their first or second quarter results or both either Intnl or US and I shall happily convert for purposes of the tables.

When I produce subsequent quarterly tables in November and February, I shall consider extra columns perhaps for age range and any suggestions for additional changes in future would be appreciated and considered by all means.

Thanking you for your time.

Hugs

Pamela

Title: Re: Comparison of our HRT Blood Test Results after 6 or 7 Months
Post by: pamelatransuk on August 31, 2018, 07:49:01 AM
Today my Endo has confirmed that despite my high E readings as detailed in the table, my E dosage will not change for another 3 months meaning I remain on Evorel Patches and Finasteride and gain Decapeptyl/Triptorelin by injection.

Hugs

Pamela
Title: Re: Comparison of our HRT Blood Test Results after 6 or 7 Months
Post by: Katie Jade on August 31, 2018, 01:48:30 PM
Quote from: pamelatransuk on August 31, 2018, 07:49:01 AM
Today my Endo has confirmed that despite my high E readings as detailed in the table, my E dosage will not change for another 3 months meaning I remain on Evorel Patches and Finasteride and gain Decapeptyl/Triptorelin by injection.

Hugs

Pamela

Hi Pamela
Yes we will then be on the same meds and dosages (From our PMs). It will be interesting to see differences. Im going to see if I can move the patches around a little as the tops of my thighs seem to be getting red during and for a while after the patches are there.
By the way I took this pic of the nurse before my first Decapeptyl Injection;

(https://i.imgur.com/BsrFMLE.jpg)

haha...

Seriously though, its a funny injection as they have to mix it, remove the bubbles and then inject it before it solidifies apparently. If they put it in the wrong place then you can feel it when you sit down.. (joking..)  :angel:

Still its only once every 3 months.

Luv n Hugz

Katie

>:-) >:-) >:-) >:-) >:-) >:-) >:-)

Title: Re: Comparison of our HRT Blood Test Results after 6 or 7 Months
Post by: pamelatransuk on September 01, 2018, 06:34:41 AM
Most amusing, Katie. You made me laugh twice!

Incidentally apart from crying at emotional events, I can truly say I am laughing more and this must be another emotional and mental benefit of HRT!

Hugs

Pamela
Title: Re: Comparison of our HRT Blood Test Results after 6 or 7 Months
Post by: pamelatransuk on September 11, 2018, 09:17:04 AM
                                   HRT Blood Test Results after 3 or 4 Months


                               E (Intnl)            E (US)       T (Intnl)       T (US)

Pamela                       922                  251               1.6              46

Sarah                         297                    81               1.1              32

Devlyn                       338                    92                4.8            140

Deborah                     261                    71                5.5            158

Kathy                         698                  190                0.2                5.8

Tonya                         224                    61                5.4            156

Katie                          364                     99               0.2                5.8

Kaitylynn                    220                     60               3.8             110

Allison                       1178                   321                1.6              47

Charlie Nicki                173                    47                5.3             154

Sadie                        2577                   702               0.4               12
   
KayXo                         974                   265               1.5               43

Casady                        821                  224                4.2             121

Kirsten                        915                   249               0.8               23

Sarahthenerd               202                     55             12.6             365



Sarahthenerd has kindly provided her 3/4 month results which I have added to the respective table. Thank you Sarah.

Hugs

Pamela
Title: Re: Comparison of our HRT Blood Test Results after 6 or 7 Months
Post by: pamelatransuk on October 02, 2018, 03:34:50 AM
                                  HRT Blood Test Results after 6 or 7 Months


                               E (Intnl)            E (US)       T (Intnl)       T (US)

Pamela                     1575                  429               2.4              69

Sarah                         349                    95               0.4              12

Devlyn                       720                   196               1.8              53

Deborah                     430                   117               4.2            120

Kathy                         303                     83              0.5               14

Tonya                         268                    73                1.1              32

Katie                          254                     69               0.2                5.8

Kaitylynn                    162                     44               1.0               30

Allison                         826                   225             <0.1             <2.5

Charlie Nicki                213                     58               2.6              74

Sadie                        1296                   353               0.4               12

Casady                      1067                   291               3.1               90

Kirsten                       422                    115               0.4               12



Casady has now provided her 6/7 month results which I have added to the respective table. Thank you Casady. 

Hugs

Pamela
Title: Re: Comparison of our HRT Blood Test Results after 6 or 7 Months
Post by: Bibi on October 16, 2018, 01:25:01 PM
5 weeks on  patch and spiro:E 58;T 169.

Bibi
Title: Re: Comparison of our HRT Blood Test Results after 6 or 7 Months
Post by: pamelatransuk on October 17, 2018, 03:35:15 AM
Hello Bibi

Congratulations on starting HRT in September; its a wonderful feeling as you take the first tablet and apply the first patch, isn't it? I think we came across each other on the Late Age GD thread in June.

Thank you very much for your E&T readings after 5 weeks; I appreciate that. Perhaps when you have been on HRT for 3/4 months in December or January, you could again post those readings please and I will gladly add yours to the 3/4 month table.

I am maintaining the tables for 3/4 months for 6/7 months for 9/10 months and for 12/13 months to see if we have any possible trends. The third table I shall start in November and the fourth I shall start in February but anytime I am happy to add readings to tables.

Thank you for your interest and hugs

Pamela
Title: Re: Comparison of our HRT Blood Test Results after 6 or 7 Months
Post by: maybesoph on October 24, 2018, 03:34:48 AM
Hi all,

U have my BT start of November for 3 month check up.
I'll provide details once I get them through, this is a fantastic idea for a thread.



Sent from my SM-G950F using Tapatalk

Title: Re: Comparison of our HRT Blood Test Results after 6 or 7 Months
Post by: pamelatransuk on October 24, 2018, 04:18:45 AM
Thank you Soph for your kind words and for "joining the table" in November.

I have having my 9 month BT on Nov 12th and should get result online on Nov 14th and soon after update the tables.

Hugs

Pamela
Title: Re: Comparison of our HRT Blood Test Results after 6 or 7 Months
Post by: Katie Jade on October 24, 2018, 03:13:07 PM
9 month BT tomorrow (a little late though) so will post them soon. feels like they have changed one or both of them.

Luv n Hugz

Katie
:-*     ;D ;D ;D ;D :P :P :P :P >:-) >:-) :angel: :angel: :angel: :angel: :angel:
Title: Re: Comparison of our HRT Blood Test Results after 6 or 7 Months
Post by: pamelatransuk on October 25, 2018, 04:19:36 AM
Thank you Katie. I am expecting my T to be down as a result of the Decapetyl/Triptorelin and for my E also to down from its previous high level. More relevantly for me, I am feeling happy and motivated thanks to HRT!

Hugs

Pamela
Title: Re: Comparison of our HRT Blood Test Results after 6 or 7 Months
Post by: VickyMI on October 31, 2018, 07:12:43 AM
So you can add me to the table.
4 months

US Based

E 56 T 6

Progynova sublingual pill and Finesteride. No blocker used.
Title: Re: Comparison of our HRT Blood Test Results after 6 or 7 Months
Post by: Marcieelizabeth on October 31, 2018, 09:55:37 AM
Pamela, is this just for the FIRST 3,,6,9,12 months then?  want to participate but not sure what is being represented...

HUGS, Marcie
Title: Re: Comparison of our HRT Blood Test Results after 6 or 7 Months
Post by: Katie Jade on October 31, 2018, 04:20:12 PM
Docs failed to take Hormone test .... not happy so have to wait another 3 weeks it seems....
Hope its worth it

Luv n Hugz

Katie

:-*   >:( >:( >:( >:( >:( >:( >:( >:( >:( :angel:
Title: Re: Comparison of our HRT Blood Test Results after 6 or 7 Months
Post by: GingerVicki on October 31, 2018, 11:35:16 PM
I want to participate, but my dates are different. I did not receive a hormone test before starting HRT. My tests will represent 2, 5, 8, 11 months. I still believe that they will be usable. I should have something to add in a few weeks. Also, my doctor is following the Callen-Lorde protocols and that will give some information that you may need. I take Spironolactone and the Patch.
Title: Re: Comparison of our HRT Blood Test Results after 6 or 7 Months
Post by: Sabrina Rei on November 01, 2018, 08:27:41 AM
My doctor at Callen Lorde told me that the transgender care industry was leaning away from consistent monitoring of hormone levels for transitioning patients, playing it by ear until things stall or something goes wrong. At which point, they would check. Have any of you heard this? He's moving on at the end of November and I will be seeing a new doctor. I wonder if it's something I should bring up?

Edit: To be clear, I haven't had any issue with my dosages or my progress but maybe I just got lucky?
Title: Re: Comparison of our HRT Blood Test Results after 6 or 7 Months
Post by: GingerVicki on November 01, 2018, 10:43:17 AM
I am all for testing every three months to make sure that everything is going as planned. Why wait until something stalls or goes wrong. Preventative maintenance makes sense.
Title: Re: Comparison of our HRT Blood Test Results after 6 or 7 Months
Post by: PurplePelican on November 01, 2018, 04:07:53 PM
Quote from: gingerViktorKay on November 01, 2018, 10:43:17 AM
I am all for testing every three months to make sure that everything is going as planned. Why wait until something stalls or goes wrong. Preventative maintenance makes sense.

Because after the initial "set up" period, once proper dosing is obtained for the patient, 3 monthly monitoring makes no sense, financially or otherwise. 6-12 month testing is all that's needed at this point.

Trans people, particularly trans women, place way too much importance on "serum levels" and ignore that the actual levels are unimportant as long as they meet certain threshold values. But then, most still operate on 90's vintage health care and are unlikely to meet those threshold levels - trans HRT is about as current as using laudanum for coughs. 
Title: Re: Comparison of our HRT Blood Test Results after 6 or 7 Months
Post by: GingerVicki on November 02, 2018, 03:37:20 AM
I am not sure how my Endo personalty identifies, but based on the beard and overall male presentation I can extrapolate that this person's identity is male. From what I understood blood test will be done periodically until levels are where they need to be. Some people need more and some people need less. How would a doctor know without tests. Anyhow, it makes sense that once levels are in the correct range to reduce testing frequency.

Quote from: PurplePelican on November 01, 2018, 04:07:53 PM
...trans HRT is about as current as using laudanum for coughs.

I understand that HRT is new and more research is needed. I also remember him saying that the HRT process is very easy.
Title: Re: Comparison of our HRT Blood Test Results after 6 or 7 Months
Post by: PurplePelican on November 02, 2018, 02:16:37 PM
Quote from: gingerViktorKay on November 02, 2018, 03:37:20 AM
I understand that HRT is new and more research is needed. I also remember him saying that the HRT process is very easy.

Trans HRT is far from new.. It was being done in the early 1900's at the Institut für Sexualwissenschaft in Berlin. You've probably seen the famous pic of the Nazi's burning the Institute's library..

However, that's not the issue.. The issue is that despite advances and research being done in other areas of medicine in regards to hormone treatments, the trans health world seems fixated on a protocol that is based as much in fallacy as it is fact.. "Too high estradiol levels cause DVT", "You need an antiandrogen to suppress T." and other such chestnuts.. These are "facts" upon which the current MTF HRT protocols are based.. The first is mostly a lie.. The 2nd is an outright lie for 90%+ of people.
Title: Re: Comparison of our HRT Blood Test Results after 6 or 7 Months
Post by: GingerVicki on November 02, 2018, 03:27:08 PM
I refer MtF HRT as new not based on the date when the technology was available, but on the usage. A sex change is still not very common.

Quote from: PurplePelican on November 02, 2018, 02:16:37 PM
... "Too high estradiol levels cause DVT", "You need an antiandrogen to suppress T." and other such chestnuts.. These are "facts" upon which the current MTF HRT protocols are based.. The first is mostly a lie.. The 2nd is an outright lie for 90%+ of people.

I've not heard of any pregnant woman getting a DVT, but other factors may be involved. High levels of Estrogen are capable of reducing T production, but I do not know of any doctor that will prescribe that much E. Honestly, I do not know how much E would be needed. Maybe it does not take much. I don't know.

Unfortunately, people have to play by the rules set forth. When I get tested then I will post results.
Title: Re: Comparison of our HRT Blood Test Results after 6 or 7 Months
Post by: gracefulhat on November 02, 2018, 07:33:05 PM
Love this thread. I will post my 4 months in early December.
Title: Re: Comparison of our HRT Blood Test Results after 6 or 7 Months
Post by: PurplePelican on November 03, 2018, 02:41:48 AM
Quote from: gingerViktorKay on November 02, 2018, 03:27:08 PM
I refer MtF HRT as new not based on the date when the technology was available, but on the usage. A sex change is still not very common.

Common or not, it's been around for quite some time. It's estimated that we have only recently started to reach the levels of understanding that the Germans had in the 30's.

QuoteI've not heard of any pregnant woman getting a DVT, but other factors may be involved. High levels of Estrogen are capable of reducing T production, but I do not know of any doctor that will prescribe that much E. Honestly, I do not know how much E would be needed. Maybe it does not take much. I don't know.

The level needed is not especially high by any means, at least not for most people. The DVT risk is almost entirely associated with oral administration, with other delivery methods the risk is about the same as the general population. This has been shown in other areas of medicine. Their are protocols out there for other medical issues that have the same end results and they are done entirely with estradiol - more importantly, they are backed by research and clinical practice.

QuoteUnfortunately, people have to play by the rules set forth. When I get tested then I will post results.

The thing about medicine is that the rules only stay the rules for as long as the majority of practitioners in the field agree and a change is coming. Slowly but surely, more doctors are moving away from the "old school" HRT protocols in light of more modern data.
Title: Re: Comparison of our HRT Blood Test Results after 6 or 7 Months
Post by: GingerVicki on November 03, 2018, 03:05:37 AM
Quote from: PurplePelican on November 03, 2018, 02:41:48 AM
Common or not, it's been around for quite some time. It's estimated that we have only recently started to reach the levels of understanding that the Germans had in the 30's.
The Germans were so very advanced in so many ways. Back then R&D meant Recover and Discover. Rest assured the governments of the world kept this information and developed it behind closed doors.

Quote from: PurplePelican on November 03, 2018, 02:41:48 AM
The thing about medicine is that the rules only stay the rules for as long as the majority of practitioners in the field agree and a change is coming. Slowly but surely, more doctors are moving away from the "old school" HRT protocols in light of more modern data.

Can you divulge some of these changes?
Title: Re: Comparison of our HRT Blood Test Results after 6 or 7 Months
Post by: TonyaW on November 03, 2018, 07:32:37 AM
Quote from: PurplePelican on November 03, 2018, 02:41:48 AM


The level needed is not especially high by any means, at least not for most people. The DVT risk is almost entirely associated with oral administration, with other delivery methods the risk is about the same as the general population. This has been shown in other areas of medicine. Their are protocols out there for other medical issues that have the same end results and they are done entirely with estradiol - more importantly, they are backed by research and clinical practice.

The thing about medicine is that the rules only stay the rules for as long as the majority of practitioners in the field agree and a change is coming. Slowly but surely, more doctors are moving away from the "old school" HRT protocols in light of more modern data.

The DVT risk with estradiol is only theoretical. Premarin and synthetic types used in oral contraceptives have shown a risk so it a precaution that really hasn't been proved or disproved. 

The drug is already on the market and available generically, so no drug company is going to lay out the cash for clinical trials regarding dosing and side effects, especially for a relatively small patient population.  With out the cash from drug company marketing, you are very correct in that it's going to take a while for any improvements to become standard treatments. 



Sent from my SM-G930T using Tapatalk
Title: Re: Comparison of our HRT Blood Test Results after 6 or 7 Months
Post by: GingerVicki on November 03, 2018, 07:44:11 AM
Quote from: TonyaW on November 03, 2018, 07:32:37 AM
The DVT risk with estradiol is only theoretical. Premarin and synthetic types used in oral contraceptives have shown a risk so it a precaution that really hasn't been proved or disproved. 

The drug is already on the market and available generically, so no drug company is going to lay out the cash for clinical trials regarding dosing and side effects, especially for a relatively small patient population.  With out the cash from drug company marketing, you are very correct in that it's going to take a while for any improvements to become standard treatments. 

Sent from my SM-G930T using Tapatalk

There is no profit in it. Drug companies just want the next big thing to make the most money possible. This is why threads like this are important. It can help someone determine if there is nothing to worry about or if a second opinion from a doctor is needed.
Title: Re: Comparison of our HRT Blood Test Results after 6 or 7 Months
Post by: PurplePelican on November 03, 2018, 03:04:19 PM
Quote from: TonyaW on November 03, 2018, 07:32:37 AM
The DVT risk with estradiol is only theoretical. Premarin and synthetic types used in oral contraceptives have shown a risk so it a precaution that really hasn't been proved or disproved. 

Actually, studies on usage have shown that oral admin of estradiol does have an increased clot risk over other delivery methods. Nothing theoretical about it. And that's also far from reason given by most doctors - who will tell you all estradiol causes stroke/DVT.

QuoteThe drug is already on the market and available generically, so no drug company is going to lay out the cash for clinical trials regarding dosing and side effects, especially for a relatively small patient population.  With out the cash from drug company marketing, you are very correct in that it's going to take a while for any improvements to become standard treatments. 

Where did I ask for a clinical trial? Where did I even suggest a trial? Oh, I didn't. A specific clinical trial is not only way to obtain the needed data. And, funnily enough, there's a fairly recent clinical trial on estradiol administration for a non-trans related condition that is just full of useful data. It also includes a comparison to a selection of antiandrogens with the aim being complete gonadal shutdown.

Use an old drug in a "new" way, you'll need a clinical trial before you can claim it's best practice.. The only real delay at this point is the glacial pace at which trans medicine seems to educate itself. I know of a member here who is/was a medical professional. they still believe all sorts of old and odd things about estradiol that are not even based in fact.
Title: Re: Comparison of our HRT Blood Test Results after 6 or 7 Months
Post by: TonyaW on November 03, 2018, 04:43:52 PM


Quote from: PurplePelican on November 03, 2018, 03:04:19 PM
Actually, studies on usage have shown that oral admin of estradiol does have an increased clot risk over other delivery methods. Nothing theoretical about it. And that's also far from reason given by most doctors - who will tell you all estradiol causes stroke/DVT.

Where did I ask for a clinical trial? Where did I even suggest a trial? Oh, I didn't. A specific clinical trial is not only way to obtain the needed data. And, funnily enough, there's a fairly recent clinical trial on estradiol administration for a non-trans related condition that is just full of useful data. It also includes a comparison to a selection of antiandrogens with the aim being complete gonadal shutdown.

Use an old drug in a "new" way, you'll need a clinical trial before you can claim it's best practice.. The only real delay at this point is the glacial pace at which trans medicine seems to educate itself. I know of a member here who is/was a medical professional. they still believe all sorts of old and odd things about estradiol that are not even based in fact.

I didn't mean to imply that you were asking for clinical trials.  Sorry if you read it that way.  I was agreeing with you that change in standard practice is slow while adding that it will be in the absence of such trials and a new (probably much more costly) drug and the marketing money behind it.



Sent from my SM-G930T using Tapatalk

Title: Re: Comparison of our HRT Blood Test Results after 6 or 7 Months
Post by: pamelatransuk on November 12, 2018, 04:56:40 AM
Quote from: VickyMI on October 31, 2018, 07:12:43 AM
So you can add me to the table.
4 months

US Based

E 56 T 6

Progynova sublingual pill and Finesteride. No blocker used.

Thank you Vicki. I shall add you to the tables which I shall update end of this week.

Hugs

Pamela
Title: Re: Comparison of our HRT Blood Test Results after 6 or 7 Months
Post by: pamelatransuk on November 12, 2018, 05:02:17 AM
Quote from: Marcieelizabeth on October 31, 2018, 09:55:37 AM
Pamela, is this just for the FIRST 3,,6,9,12 months then?  want to participate but not sure what is being represented...

HUGS, Marcie

Thank you Marcie and Yes it is for the first 3,6,9,12 months and I am updating end of this week for 3,6,9 months and in February I shall complete 12 month table. I shall examine and consider whether it is worthwhile to continue after February or not.

You can either PM your previous results to me or post them on this thread. I calculate the conversion. Either way I am most grateful.

Hugs

Pamela

Title: Re: Comparison of our HRT Blood Test Results after 6 or 7 Months
Post by: pamelatransuk on November 12, 2018, 05:15:48 AM
Quote from: GingerVicki on October 31, 2018, 11:35:16 PM
I want to participate, but my dates are different. I did not receive a hormone test before starting HRT. My tests will represent 2, 5, 8, 11 months. I still believe that they will be usable. I should have something to add in a few weeks. Also, my doctor is following the Callen-Lorde protocols and that will give some information that you may need. I take Spironolactone and the Patch.

Thank you GingerVicki. I look forward to seeing your BT results in due course and I shall add them to the tables.

Hugs

Pamela
Title: Re: Comparison of our HRT Blood Test Results after 6 or 7 Months
Post by: pamelatransuk on November 12, 2018, 05:18:32 AM
Quote from: gracefulhat on November 02, 2018, 07:33:05 PM
Love this thread. I will post my 4 months in early December.

Thank you for your kind words, Gracefulhat. I look forward to seeing your BT results in due course and I shall add them to the tables.

Hugs

Pamela
Title: Re: Comparison of our HRT Blood Test Results after 6 or 7 Months
Post by: pamelatransuk on November 12, 2018, 08:29:32 AM
Quote from: Katie Jade on October 31, 2018, 04:20:12 PM
Docs failed to take Hormone test .... not happy so have to wait another 3 weeks it seems....
Hope its worth it

Luv n Hugz

Katie

:-*   >:( >:( >:( >:( >:( >:( >:( >:( >:( :angel:

Sorry to hear Katie you were unable to have your bloods drawn in October. I hope you may have them drawn next week and that you receive pleasing results.

I am having my BTs today and shall update the tables at the end of this week. Please PM me your results when you read them online or when you receive notification from GP and I shall happily add yours to the tables then. Thanking you.

Hugs

Pamela  xx
Title: Re: Comparison of our HRT Blood Test Results after 6 or 7 Months
Post by: GingerVicki on November 12, 2018, 02:24:54 PM
With reading this thread I wonder if I will be getting the hormone tests. I did not get one before starting and quite frankly the changes are obvious. I am not sure if I really need one done.
Title: Re: Comparison of our HRT Blood Test Results after 6 or 7 Months
Post by: Katie Jade on November 26, 2018, 12:20:14 PM
results 26/11/18 - 10 months

Serum testosterone level < 0.2 nmol/L [8.3 - 27.8]

Serum oestradiol level 223 pmol/L [95.0 - 223.0]

so dropped from last tests despite increase of dosage

luv n hugz

Katie

:-*      ;D ;D ;D ;D ;D ;D ;D ;D ;D :angel: :angel: :angel: :angel: :angel: :angel:
Title: Re: Comparison of our HRT Blood Test Results after 6 or 7 Months
Post by: pamelatransuk on November 27, 2018, 04:39:23 AM
Thank you Katie for your results which I am transferring to the 9/10 Months thread.

Hugs

Pamela
Title: Re: Comparison of our HRT Blood Test Results after 6 or 7 Months
Post by: fgsb on November 27, 2018, 09:27:10 AM
Finally got my 4 month results back!!!

I started at (07/06/2018) T= 346 and E= 23

After 120 days (11/01/2018), I am at T= 37.3 and E= 116.6


Going to be 38 in December
Title: Re: Comparison of our HRT Blood Test Results after 6 or 7 Months
Post by: pamelatransuk on November 28, 2018, 04:24:19 AM
Thank you fgsb for your results which I am transferring to the 9/10 Months thread.

I appreciate your results are for 4 months but I use the latest thread which now is the 9/10 Months thread to update the 3 tables.

Hugs

Pamela
Title: Re: Comparison of our HRT Blood Test Results after 6 or 7 Months
Post by: Veracious Valerie on December 08, 2018, 12:21:28 PM
I have been o HRT for 4 months now.
1st month was just a low dose of E.
2nd month doubled my E.
3rd month started Spiro.
5th month. In a week I go back in to talk about my latest blood results. Here they are...

Day -10(Days before starting any meds) Aug 09th
Testosterone=392 ng/dL
Estradiol=17 pg/mL

Day 30 Sep 19th
Testosterone=201 ng/dL
Estradiol=58 pg/mL

Day 109 Dec 7th
Testosterone=48 ng/dL
Estradiol=145 pg/mL

:)

Quote from: fgsb on November 27, 2018, 09:27:10 AM
Finally got my 4 month results back!!!

I started at (07/06/2018) T= 346 and E= 23

After 120 days (11/01/2018), I am at T= 37.3 and E= 116.6


Going to be 38 in December

I am 37. Turn 38 on International women day (March 8th)  :)
We are very similar. That is nice to see.
Title: Re: Comparison of our HRT Blood Test Results after 6 or 7 Months
Post by: pamelatransuk on December 10, 2018, 04:51:11 AM
Thank you Veracious Valerie for your results which I am transferring to the 9/10 Months thread.

I appreciate your results are for 4 months but I use the latest thread which now is the 9/10 Months thread to update the 3 tables.

Hugs

Pamela