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Community Conversation => Transsexual talk => Male to female transsexual talk (MTF) => Topic started by: Asakawa on January 28, 2019, 12:35:19 AM

Title: Safety difference between oral vs injectable estrogen w scientific evidence?
Post by: Asakawa on January 28, 2019, 12:35:19 AM
Hello

Does anyone know of any good scientific articles pointing out the safety difference between oral and injectable estrogen? I need some I can print out to show my doctor because he has me on high dose oral and I want him to switch me to injectables. I am hoping that with this I can convince him to switch me to injectables. I need something that hopefully is not too huge in info so I don't have to print out too many copies and scare him away from looking at them. I really want to switch to injectables but he is hesitant about it. If anyone knows of any good scientific articles could you please share them with me? I need something that prints out of a legitimate website and not quotes from forum postings.
Title: Re: Safety difference between oral vs injectable estrogen w scientific evidence?
Post by: Harley Quinn on January 28, 2019, 06:39:41 AM
If you look in the Hormones section, there are tons of articles and links to the PubMed sources.
Title: Re: Safety difference between oral vs injectable estrogen w scientific evidence?
Post by: Ann W on January 28, 2019, 10:19:03 AM
Quote from: Asakawa on January 28, 2019, 12:35:19 AMI really want to switch to injectables but he is hesitant about it.

I don't want to trouble you further, but I was already on oral estrogen when I started seeing an endocrinologist in October, 2017. I inquired about injections early in our relationship, and it took about nine months before he would prescribe them -- because he had never done so before. And when he did, the dosage he put me on was ludicrous. I asked around, and learned that the dosage he prescribed was what was on the package insert of the medication -- a medication created for post-menopausal cis-women (who don't need to feminize), not for us. I switched doctors.

I read an article recently that said that a lot of endocrinologists don't know how to treat trans women. We fall within their area of specialization, but not necessarily their expertise.
Title: Re: Safety difference between oral vs injectable estrogen w scientific evidence?
Post by: AnneK on January 28, 2019, 10:39:52 AM
Quote from: Ann W on January 28, 2019, 10:19:03 AM
I read an article recently that said that a lot of endocrinologists don't know how to treat trans women. We fall within their area of specialization, but not necessarily their expertise.

I'll be going to one that does this sort of work.  However, I'll be on pills, as that's what the drug plan covers.
Title: Re: Safety difference between oral vs injectable estrogen w scientific evidence?
Post by: Randi on January 28, 2019, 01:21:27 PM
A person over 60 should never take oral estrogen.  It's quite risky. Hard on the liver and more likely to cause DVT.

Injectable Estradiol is relatively cheap. It will cost around $50 for a 10 week supply, using discount coupons which are readily available 

Estrogel while, is a bit more expensive, $106 / month.

The insurance doesn't offer you much advantage, since Walmart will sell generic estradiol tablets @ $10 for a 90 day supply.

I just read that you are in Canada, where injectable estrogen just isn't available except form a compounding pharmacy.  I'm not sure about patches or gel.

Title: Re: Safety difference between oral vs injectable estrogen w scientific evidence?
Post by: AnneK on January 28, 2019, 01:25:35 PM
QuoteA person over 60 should never take oral estrogen.  It's quite risky.

I'll have to see what the endocrinologist says.  That's what the informed consent is about.
Title: Re: Safety difference between oral vs injectable estrogen w scientific evidence?
Post by: Sabrina Hope on January 28, 2019, 04:39:06 PM
I live in Canada and I am able to find injectable estrogen. I have <dosage removed> solution and I inject <dosage removed> per week. All forms of estrogen are available here and my doctor let me choose the form I want.