Transgender and Without a Trace
http://hons3304h03.blogspot.com/2008/06/transgender-and-without-trace.html
I just finished watching an episode of Without a Trace. In this particular story, the missing person was a women who underwent a gender reassignment surgery. The woman at one point led a "normal" life of a male, complete with a wife and two kids. At first, the FBI agents and detectives thought the woman was a victim of a hate crime because of someone's disjointed and disgusted view of transsexuals.