What exactly is hrt doing inside my body? How does the pills work? Is the testerone blocker..fighting against all testerone all day, or just a couple of hours till u take ur second dose? I started to wonder about this, as i take 7 doses a day of spiro nd estridol nd medroxy.
there are certain receptors in the body that accept the hormones. Spiro blocks the production of testosterone. Some of the receptors will receive the estrogen and progesterone. When one takes the medication, it keeps the levels up where they need to be.
7 doses per day?
Any room left for food?
How Do Hormones Work?
http://www.pbs.org/wgbh/pages/frontline/shows/nature/etc/hormones.html (http://www.pbs.org/wgbh/pages/frontline/shows/nature/etc/hormones.html)
Quote from: juliemac on May 29, 2011, 06:33:32 PM
7 doses per day?
That seems to be a very unusual regimen. Do you have any idea why your doctor has broken XX mg of spiro and yy mg of estradiol per day into 7 doses? The usual pill regimen is one dose per day. You must spend a lot of time splitting tiny pills into tinier bits and pieces.
Robyn
No lol. U all have it wrong. I take 4 estrodiol pills a day. With the spiro, i take two daily and progesterone, one daily. in all 7 pills each day. Sorry if i confused u all...
In your body certain cells have "Androgen Receptors" Poking out of their surface. like hair follicles, but also cells in your layrinx and penis and testisicles. Testosersone is a growth factor it comes in binds to those androgen receptors and encourages many different behaviours.
Like it might encourage hair follicle cells to grow and divide causing body and facial hair but on other cells like scalp hairs it's acts as an inhibitor to growth stopping cell cycle and encouraging apoptosis these cause on the large scale the changes accociated with the male puberty.
When you take a hormone blocker it ends up floating around your blood stream, it then sticks to this androgen receptor on those cells and stuffs it up breaking it the body will gradually replace the androgen receptors. without this "growth" signal certain cells can't live without it and undergo cell apoptosis. But some just stop growing so fast instead now reliant on other hormones such as EGF or other growth factors.
While some cells have androgen receptors others have "estrogen receptors" largely fat cells but some other cells too. That obscure ridge down the central line of your penis... Breast cells, Fat cells. When you expose those cells to estrogen they are encouraged to divide and grow. on the macroscale it manifests as breast development and the other changes we get.
The pituitary gland detects either estrogen or testosersone it dosen't care whitch you have circulating but will detect a normal level of "steroid" hormones and send shutdown signals to the gonads.