I currently inject.  However, I used gel for a short period, liked it, but it is very expensive.  Putting it on is a very sensuous act.  I used patches for years.  Less expensive, but I am prone to eczema, sort of a minor red rash.  The patches also leave a slightly sticky residue that is hard to get off.  I never felt quite as smooth while using them compared to gel or the injections.  It wasn't terrible though.  Some girls seem to have a problem during the summer, while outdoors, and having them fall off from sweating.  I work inside and that was never a problem for me.  It is my understanding that all methods of estrogen intake work just as well,  although some users swear about the efficacy of one over another.  I believe that it is just cost and ease of administration that makes a difference.  Good luck.