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Switching to transdermal patches

Started by Alana Ashleigh, July 28, 2025, 04:37:26 PM

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Tills

I'd just like to reiterate though, staying on topic, that generally I think the patches are fantastic. Compared to the gels I was smearing on twice a day, the patches have transformed my life and quality of life.

xx

Charlotte_Ringwood

I'd love to go on to patches myself. They are just very expensive. I think I'll move to them when I'm not having to spend on laser removal, surgery and such. Or I'll jus wait a few years until I can get through NHS.

Good to know that you rate them so highly. I love the idea of them
People tell me I'm successful, kind, amazing, I talk sense and got it all together.  Only some see the real tenuous paper thin foundation behind it. The terrified child protecting herself. But I'm strong. I'm gonna be better. I'm gonna start doing life for me. Not what I think others want me to be. Love Charlotte 😻
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Tills

Today was changeover day so I've switched up to Evorel 100. In the extremely unlikely event that I feel off colour I'll peel off the extra mini patch.

But I'm expecting my transgender clinic and GP surgery to approve this in a few weeks time.

Bear in mind that my trough reading on gels was 400 pmol/L so 131 pmol/L really is a dip.

xx
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Courtney G

I did lots of stuff to manipulate my dosage while using patches. Early on, I cut them in halves or quarters in order to microdose and later I left some patches on for a couple of extra days after I added new ones, creating an "overlap" to increase my effective dose. It was also a means to allow me to stockpile patches.

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Tills

Thanks @Courtney G : that's helpful to know. I hadn't thought about leaving the previous one on to create an overlap.
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Tills

In terms of stockpiling, I have some extra patches as whilst I awaited the GP surgery to connect with my clinic I ordered a private prescription through the post. Nothing dodgy about that: a bona fide UK pharmacy who checked that my clinic had approved it. It's useful to have the extras as I hate running low.

@Charlotte_Ringwood I bought 16 x Evorel 75 for £25. I suppose that is quite pricey but if you're doing 2 a week (mine is 2 in 6 days) then it's roughly £13 a month. Not too bad?

xx

Charlotte_Ringwood

Quote from: Tills on January 30, 2026, 07:28:53 AM@Charlotte_Ringwood I bought 16 x Evorel 75 for £25. I suppose that is quite pricey but if you're doing 2 a week (mine is 2 in 6 days) then it's roughly £13 a month. Not too bad?

xx

Doesn't sound so bad...just not sure of equivalent dose as I'm on 6mg oral per day to get my levels. Might need two patches to get it. I'll have a look again. Thanks 😊
People tell me I'm successful, kind, amazing, I talk sense and got it all together.  Only some see the real tenuous paper thin foundation behind it. The terrified child protecting herself. But I'm strong. I'm gonna be better. I'm gonna start doing life for me. Not what I think others want me to be. Love Charlotte 😻
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Courtney G

Quote from: Tills on January 30, 2026, 07:22:35 AMThanks @Courtney G : that's helpful to know. I hadn't thought about leaving the previous one on to create an overlap.

You're welcome. I'll add that near the end of my time with patches just a month ago, I decided to stagger them to create a shallower trough. I was using four .100 mg patches twice a week and I think my peak was ok but my trough too low, so I did something like this:

Monday night: 3 patches (instead of 4). Maybe leave one patch on from the previous dosing, creating a four patch dose (effectively)
Wednesday evening or Thursday morning. Add one patch. Remove the "overlap" patch if used
Friday morning: 3 patches, same as Monday

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Tills

Sure enough, my clinic have requested to my GP an increase from Evorel 75 to Evorel 100.

The covering letter says this, which I found interesting: this is the first time I've seen my clinic or anyone within the NHS pick up on the idea mentioned upthread by others about application to the trunk. I may well go for that as one of my alternating sites I think.

I'm copying most of the letter because I think the context is important:

'Thank you for forwarding on a copy of the latest blood investigations which show a lower than ideal oestradiol level of 131pmol/L.

Treatment plan

We would be most grateful if you would amend treatment as below:

•   Please increase Evorel twice weekly patches from Evorel 75 to Evorel 100mcg/24hr
Patches should be applied to clean unbroken skin to the trunk below the belly button or the top of the thighs.

•   10 weeks after increasing this dose of Estradiol patches please carry out the following blood investigations:

Oestradiol, Testosterone, LFT's, LH, FSH, SHBG and Prolactin
It is important that blood investigations are carried out approximately 48 hours after patch application.

We are aiming for an Oestradiol level in the range of 400-600pmol/L.'


I still love the patches in terms of their ease of application and lack of intrusion, a marked contrast to the gels.

xx

Tills

I'm getting increasingly tired of NHS England and the bullying and anti-trans note of this Labour Gov't.

So after my Transgender Clinic requested my GP to increase my dose from Evorel 75 to Evorel 100, the GP Surgery insisted on an appointment and put this on my notes:

'11 February 2026 12:14 pm
SURGERY -
Comment
• Patient requesting Evorel 100. Recommended by Nottingham Centre for Transgender Health.
• Amber on Surrey Pad.
• Shared care agreement required.
• 06 Dec 23 - Surrey Heartlands Integrated Care System Area Prescribing Committee (APC); After undertaking a review of previous decisions and resources relating to transgender health, the APC agreed an AMBER status for ostrogen, testosterone, cyproterone, finasteride, GnRH & medroxyprogeterone when used in adults.;; Primary care initiation of these drugs is supported by the APC if the prescriber is competent to exercise their share of clinical responsibility and is assured that the shared care protocol provides enough information for them to discharge their responsibilities safely.;; A guide to support primary care prescribing for people who access gender identity services was also agreed by the APC.;; The guide includes information on children and young people, requests to prescribe, shared care, on-going care and private providers.
• A+G sent to clinic today requesting SCA.'

This is all very Gatekeepery but above all it's just a giant waste of time. I've been under Nottingham GiC for 14 years. I've also requested them to take this unnecessary addition off my notes, citing my GRC. My GP already knows this is Amber status but that because it comes from the GiC that is covered, and actually irrelevant in my case.

I think it's partly because this GP surgery, which is a new one for me, aren't familiar with care for people like me.

Sigh.

Sorry. Just annoyed. I could continue this rant into the diabolical state of how to get an appointment and 'online triage' brought in by that slimy anti-trans slug Wes Streeting.

Meantime I've ordered 3 months supply from a private pharmacy online as I like having a stock for precisely this sort of NHS faffery and bureaucracy.

Vent over. For now. ;)

xx
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Tills

I hope Scotland's better because I feel like moving to another country right now
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Charlotte_Ringwood

The state of the NHS is dire to be honest. They've left with me with no mental health support and waiting lists for gender related care. So not surprised to hear your story. I get your frustration!

I'm just glad I'm totally DIY and doing everything else privately. Just leaves in thousands of debt!

I hope you get everything sorted soon x
People tell me I'm successful, kind, amazing, I talk sense and got it all together.  Only some see the real tenuous paper thin foundation behind it. The terrified child protecting herself. But I'm strong. I'm gonna be better. I'm gonna start doing life for me. Not what I think others want me to be. Love Charlotte 😻