Study shows testosterone therapy does not increase anger, irritability...

[Jessica_Rose ✅]

Study shows testosterone therapy does not increase anger, irritability, or aggression in trans youth

https://www.lgbtqnation.com/2026/03/study-shows-testosterone-therapy-does-not-increase-anger-irritability-or-aggression-in-trans-youth/ 🔗

Greg Owen (7 March 2026)

A new study on the effects of testosterone therapy on transmasc youth found that those who initiated the hormone treatment do not, on average, experience increased anger or irritability a year later.

The study, published this week in the Journal of Adolescent Health, addresses a common concern by trans youth and their families that increased anger, irritability, or aggression could be a side effect of testosterone therapy.

False claims have spread about soaring numbers of mass shootings committed by trans shooters, when most have been carried out by cisgender white men.

"Put simply, transgender individuals account for a vanishingly small proportion of perpetrators," says James Densley, co-founder and deputy director of the Gun Violence Archive.

The testosterone study was conducted by nine researchers affiliated with major children's hospitals in the U.S., including the Ann & Robert H. Lurie Children's Hospital of Chicago, Boston Children's Hospital, and Benioff Children's Hospital at the University of California, San Francisco. It included 178 transgender and gender diverse adolescents and young adults across four major gender care centers in the United States who initiated testosterone therapy.

The participants were 12-20 years old with an average age of 16.

92% identified as transmasculine/male, and 58% were white. All the subjects had completed puberty and had no exposure to puberty blockers.

The study found that, on average, self-reported levels of anger, aggression, and irritability were within normal ranges at the start of testosterone therapy (referred to as baseline) and remained about the same 12 months after initiation.

[Athena]

My family has a history of anger issues. I spent most of my life fighting my anger, I was afraid that if I lost control I would really hurt someone.
To be fair testosterone is a poison for me but once I started hrt my anger issues seemed to evaporate.

 This one situation while I was riding a bus and this guy just wouldn't shut up and it was like nails on a chalkboard. Before hrt I would have wanted to dismember him with my bare hands and I would have struggled to not do that. Luckily I was on hrt and even though it was still a struggle to not act I just wanted to wrap duct tape around his head to shut him up which for me is a vast improvement.

Now my anger issues were an inherited problem but I don't know if my hormone incompatibility made things worse. I haven't talked to my dad in over 20 years so I don't know how mine compare to the rest of my family.

[Lori Dee ✅]

The participants were 12-20 years old with an average age of 16.

... All the subjects had completed puberty and had no exposure to puberty blockers.

Completed puberty at 12? When did they start, at 6?

@Athena

I never believed that hormones cause any emotions at all. I think they make us feel them more intensely if they are already there. With a history of anger issues, testosterone could affect that, just as reducing T or eliminating it reduced its effects.

And it's not you. There are people in this world that need duct tape... a lot of duct tape.

OK, maybe not. 🤣