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Klinefelters Syndrome

Started by Stottie Girl, May 16, 2026, 09:49:21 AM

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Stottie Girl

Quote from: CosmicJoke on Yesterday at 10:11:45 AMI think pretty much any combination of chromosomes that are Y will have you legally considered "male" at birth.

When I went through my first puberty I had 266 ng/dl of testosterone. I had a "normal" amount of testosterone. I attributed the hair growth and growth spurts I was having to that. Besides that there really wasn't much "masculinizing."

I don't think you can necessarily tell what someone's hormone levels are just by looking at them. I think that would vary greatly depending on the person's sensitivity to that hormone. You would have to do a blood test to know for sure. I also think intersex conditions are much the same. You have to do an MRI or some other test to know for sure.


As far as I can tell you have to give blood for a karotype analysis as per what Nancy has said above. Ultimately I feel the only benefit of this would be to satisfy curiosity. I'm not sure it will truly benefit me knowing. There are several other ways you can be intersex other than Klinefelters Syndrome too. Apparently you do not have to be super tall to have that condition it will make you taller than what you were genetically pre-disposed to be but if your family were all shorter this could mean you don't get above 6'.
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Lori Dee

There is little logical reasoning to take the test. You can do it at home yourself.

Sex Determination: The SRY gene (Sex-determining Region Y) on the Y chromosome triggers the development of testes in an embryo. Without this gene, a fetus will develop female reproductive organs.

So, if I look down, I can see that clearly a Y chromosome was present during my fetal development.

But there are other conditions that can also affect an intersex condition. It is possible to have both male and female organs. That is something a Y-chromosome won't tell you.

Then there is AIS (Androgen Insensitivity Syndrome) where the body has the Y-chromosome, testes are present but the body is essentially immune to the effects of testosterone. This results in a body with feminine shape and appearance, except for those dreaded dangly bits.

There are many other possibilities, and Kleinfelter's is only one of them. For most of us, the only thing the test will tell you is if you have multiple X's along with your Y. That really doesn't answer most of the questions we have.
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Stottie Girl

Quote from: Lori Dee on Yesterday at 01:22:52 PMThere is little logical reasoning to take the test. You can do it at home yourself.

Sex Determination: The SRY gene (Sex-determining Region Y) on the Y chromosome triggers the development of testes in an embryo. Without this gene, a fetus will develop female reproductive organs.

So, if I look down, I can see that clearly a Y chromosome was present during my fetal development.

But there are other conditions that can also affect an intersex condition. It is possible to have both male and female organs. That is something a Y-chromosome won't tell you.

Then there is AIS (Androgen Insensitivity Syndrome) where the body has the Y-chromosome, testes are present but the body is essentially immune to the effects of testosterone. This results in a body with feminine shape and appearance, except for those dreaded dangly bits.

There are many other possibilities, and Kleinfelter's is only one of them. For most of us, the only thing the test will tell you is if you have multiple X's along with your Y. That really doesn't answer most of the questions we have.

Plus it isn't cheap! You will have to be very curious to pay the money I think. I probably am that curious but I don't have hundreds of pounds to spare ha ha!
A wise man once said don't judge a man until you've walked a mile in his shoes, that way when you judge him you're a mile away and you have his shoes!

Never trust a man who, when left alone in a room with a tea cozy, doesn't try it on - Billy Connolley

NancyDrew1930

Quote from: Lori Dee on Yesterday at 01:22:52 PMThere is little logical reasoning to take the test. You can do it at home yourself.

Sex Determination: The SRY gene (Sex-determining Region Y) on the Y chromosome triggers the development of testes in an embryo. Without this gene, a fetus will develop female reproductive organs.

So, if I look down, I can see that clearly a Y chromosome was present during my fetal development.

But there are other conditions that can also affect an intersex condition. It is possible to have both male and female organs. That is something a Y-chromosome won't tell you.

Then there is AIS (Androgen Insensitivity Syndrome) where the body has the Y-chromosome, testes are present but the body is essentially immune to the effects of testosterone. This results in a body with feminine shape and appearance, except for those dreaded dangly bits.

There are many other possibilities, and Kleinfelter's is only one of them. For most of us, the only thing the test will tell you is if you have multiple X's along with your Y. That really doesn't answer most of the questions we have.


Not always.  In my case they thought I might've been a XX female as well with an attached SRY section (they are also wondering if I have AIS, but that was put on the back burner) from a Y chromosome (but not have a Y).  But on the Y chromosome the SRY sequence is the main part that gives the instructions for creating the testicles and it occasionally breaks off and attaches to a X chromosome.
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