Oh gosh who knows, if she gets to stay alive so does Jimi, maybe they would have recorded together. Or she could have other bands back her up. Blues requires both vocals and instruments - half of the near eternal goodness that is those early Janis records is Big Brother & the Holding Co. So she'd need a hot guitar player, or a hot harp player, or a whole bunch of hot players. Her bands kept getting better - Full Tilt Boogie Band was tight. Or she could have picked up hot young bands to back her up. Imagine Janis with a young Pearl Jam, a young Nirvana, or a young Black Crows (that would rock) - or backed up by old Jerry, or old Neil, or Stevie Ray Vaughan.
Of course she could have just retired (lots did), or wound up on the county fair circuit, or a low level Vegas show - show biz is a very bitchy mistress.