The 11th annual Philadelphia Trans Health Conference is the largest trans health conference in the US (and probably the world). It's happening in just a few weeks: May 31st through June 2nd, at the Philadelphia Convention Center.
At this event, "health" is defined in its broadest sense. Workshop topics include transgender basics; spirituality; the most diverse surgery show & tells; youth and families programming; sexuality; non-binary gender; mental health; sessions for partners; etc etc etc. Along with all that, there are free medical exam appointments (through Mazzoni Center); low cost food options; possibilities for community housing; and oh my goodness social events. There is special programming for children who are trans, as well as their families. There is an education track for mental health and medical providers, where some of the best people (therapists and surgeons) train providers who want to learn or gain expertise in caring for our communities. (Provider attendance has a registration fee, and CEUs are available.)
I'm glad to answer questions here or via PM. I've attended nearly all since the first one, as participant as well as presenter. It's a conference that's gotten better and better each year, and I wouldn't miss it.
More info, and the registration page (free, but please register since it helps them plan printing and rooms and staffing) is here:
http://www.trans-health.org/about If it helps sweeten the deal at all, ComicCon is happening the same weekend, elsewhere in the convention center.