Not afraid, but we have more Black Widows, scorpions, and brown recluses around here than you can shake a stick at!
We get the scorpions in the house a lot, and the rest everywhere else (along with the scorpions).
I'm rebuilding our deck right now, and while I was concerned about finding a rattlesnake den under it - when I got to tearing into it - it turned out to be a Widow's Ball instead.
Anyhoo - not afraid, but cautious about where I stick my hands and feet.