I seriously doubt it will, but thinking of it... wow, maybe it might.
But either way, if you want a successful transition, testosterone needs to die, and as soon as possible, be it with anti-androgens or an orchiectomy. Or some people report that just estradiol kills their testosterone more than enough, but I don't know about that. Testosterone will keep slowly but surely worsening your appearance until you die if your testosterone levels stay in the male range.
But if your testosterone is assassinated properly, then the risk of regrowth is probably zero. Though there's a chance it's zero as well even with male levels. I can't say for sure.
