I think he makes a lot of good points, too. I think we as trans people, can be elitist sometimes with our expectation for "regular" folks to be up to speed with trans issues. I'm still coming out to a lot of people, and I'm openly... open to questions. I know people will use the wrong terminology. I know people will use the wrong pronouns. I know people will ask questions that will seem either bigoted or bone-headed. It's not because people mean ill to any of us. They just don't know -- and that's okay!
If somebody is asking a question, even if they phrase things wrong, it's because they genuinely want to know. Here's a guide: feel the intent behind the question. Is the intent pure, but there's a mish-mash of words? Address the question first, and handle the verbal blunder as an afterthought.
But we don't have to walk the world with the utmost poise, either! If you get a, "what the ->-bleeped-<- is you?" like I do on a regular basis, go ahead and use that caustic wit of yours to shove it in their face.
Lastly, the single most offensive question a person can ask: What's your favorite Nicolas Cage movie?