I noticed...something after starting E. Like something in my head, but I can't put a finger on it. I don't want to call it calmness, because it doesn't feel that way to me. I wish I could explain it better, but certainly it feels different. Like the feeling started minutes after dissolving under my tongue, and I have no words for it.
Still all other physical changes take more time than 30 minutes, but you will be surprised how quickly your skin softens.