Does spironolactone have feminizing effects?

[E-Brennan]

Just wondering, does spironolactone have any noticeable feminizing effects?  I've searched and found little information, and what information there is tends to be conflicting.

Any personal experiences in whether spiro does much on its own?

I ask because my endo is going to put me on spiro for a while first before bringing estrogen into the equation.  A cautious approach - frustrating too, seeing as I'm way past ready to get started with HRT - but I need to remind myself once every so often that it's not a race but a long, slow process.

[kira21 ♡♡♡]

It can do. If you look on the list of possible side effects then it will talk about gynecomastia (breast formation).  I would guess that it could also have a mild effect on hair too.  I would not expect a massive amount of feminisation though.

[Cindy]

As you know spiro is an AA, stopping T will lead to some feminisation but usually I put someone on a AA first if I think they may not tolerate E. That may be health as in weight, BP, LFT or lifestyle or in mental/life style tolerance. I was put on E without AA for the same reasons. There are no strict rules.

[E-Brennan]

Info appreciated.  Thanks.

[Amy1988]

Just wondering, does spironolactone have any noticeable feminizing effects?  I've searched and found little information, and what information there is tends to be conflicting.

Any personal experiences in whether spiro does much on its own?

I ask because my endo is going to put me on spiro for a while first before bringing estrogen into the equation.  A cautious approach - frustrating too, seeing as I'm way past ready to get started with HRT - but I need to remind myself once every so often that it's not a race but a long, slow process.

Also could those who have been taking spiro share how effective it has been in reducing T levels? I was prescribed it yesterday at a starter dose.  I've read that the T that is blocked from receptors and just floating around in the body get converted to estrogen.

no dosages please

[KayXo]

Spiro reduces/inhibits T and since you won't be taking any estrogen to replace the lost T, you may have symptoms related to lack of sex hormones such as hot flashes, experience depression/irritability, not feel good, weak/tired, unmotivated etc. If you come across those, you should advise your doctor immediately.

On Spiro, make sure to drink plain water as much as you want and eat as much salt as you crave since Spiro reduces sodium in the body. Also, limit potassium intake so try and avoid high potassium drinks/foods/supplements. Moderate your intake of diuretics as well.