Quote from: Claire (formerly Magdalena) on June 06, 2014, 04:38:03 PM
I was told all E did... I'm on the patch now and it hasn't killed me, you may have more accurate info. 
J Urol. 2005 Aug;174(2):527-33; discussion 532-3.
Transdermal estradiol therapy for prostate cancer reduces
thrombophilic activation and protects against thromboembolism"PURPOSE: Oral estrogens were an effective treatment for prostate
cancer but were abandoned because of an increased risk of
cardiovascular toxicity and particularly thromboembolism. We have
recently shown that transdermal estradiol produces an effective tumor
response and negligible cardiovascular toxicity. Here we report the
influence of transdermal estradiol therapy on the coagulation profile
of men with advanced prostate cancer. "
"CONCLUSIONS: These results suggest that transdermal estradiol reduces
thrombophilic activation in men with advanced prostate cancer, and
protects against the risk of thrombosis."
I also think similar results have been found in women treated with transdermal estradiol. Very good news indeed.