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8 months and UGH

Started by HeatherR, July 14, 2014, 11:34:33 PM

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HeatherR

July 14, 2014, 11:34:33 PM
So, I hit the 8month consecutive mark, and my labs just came back..  Not happy...


Estradiol:        65 pg/mL
Testosterone: 44 ng/dL

No wonder I feel like poo..  Testosterone is old man status, and Estradiol is old woman status  :(
The obstacles of your past can become the gateways that lead to new beginnings.  ~Ralph Blum~
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mrs izzy

#1
July 14, 2014, 11:43:28 PM
Hang in there. You will be on hrt all your life and its better to work at the balance then rush.

Frustrating I know but its way better then before you started.

Always something of positive.

Just keep working on the goals of you and your doctors.

Safe is life.

Izzy
Mrs. Izzy
Trans lifeline US 877-565-8860 CAD 877-330-6366 http://www.translifeline.org/
"Those who matter will never judge, this is my given path to walk in life and you have no right to judge"
I used to be grounded but now I can fly.
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HeatherR

#2
July 14, 2014, 11:47:28 PM
My estradiol level is up from my 3month lab, but only by a few points.  My T is only a little lower than baseline...  I'm on a pretty high dose (pill) of both estradiol and spiro.  I told my doctor before starting that I am almost entirely immune to oral medication.  I've never taken an oral medication that had any measurable effect on my body.  Thus I am willing to bet I almost completely metabolize it with a first pass through the liver.

Much to my chagrin, he kept the dosage the same from 3rd to 6th month despite my informing him of my super liver.  I'm both slightly dismayed, given I just received word that he is closing his practice, but also optimistic that the doctor in which he has referred my care, will take my findings and previous experience to heart.
The obstacles of your past can become the gateways that lead to new beginnings.  ~Ralph Blum~
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KayXo

#3
July 15, 2014, 10:41:41 AM
Yup, that level seems pretty low. My levels are way above 1,000 with injectables (up to 4,000) and I'm doing great, much better than on oral. Hopefully, new doctor will find a way to get levels a little higher if they deem it safe and effective for you. Good luck. ;)
I am not a medical doctor, nor a scientist - opinions expressed by me on the subject of HRT are merely based on my own review of some of the scientific literature over the last decade or so, on anecdotal evidence from women in various discussion forums that I have come across, and my personal experience

On HRT since early 2004
Post-op since late 2005
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HeatherR

#4
July 15, 2014, 12:18:51 PM
Thanks Kay:)
The obstacles of your past can become the gateways that lead to new beginnings.  ~Ralph Blum~
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HeatherR

#5
July 15, 2014, 12:19:37 PM
It explains why I am constantly sweating and gaining weight in my belly on low cal diet
The obstacles of your past can become the gateways that lead to new beginnings.  ~Ralph Blum~
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KayXo

#6
July 15, 2014, 01:05:30 PM
I don't think low cal diet is good for the body, you are starving it perhaps of what it needs. And a body lacking nutrients, energy won't be able to develop optimally on hormones. Just my 2 cents...;)
I am not a medical doctor, nor a scientist - opinions expressed by me on the subject of HRT are merely based on my own review of some of the scientific literature over the last decade or so, on anecdotal evidence from women in various discussion forums that I have come across, and my personal experience

On HRT since early 2004
Post-op since late 2005
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HeatherR

#7
July 15, 2014, 02:47:47 PM
I'm eating balanced meals, just not 2500 calories
The obstacles of your past can become the gateways that lead to new beginnings.  ~Ralph Blum~
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Thylacin

#8
July 15, 2014, 05:57:11 PM
Are you taking the estradiol pills sublingually or swallowing them?
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Thylacin

#9
July 15, 2014, 06:00:55 PM
Quote from: KayXo on July 15, 2014, 10:41:41 AM
Yup, that level seems pretty low. My levels are way above 1,000 with injectables (up to 4,000) and I'm doing great, much better than on oral. Hopefully, new doctor will find a way to get levels a little higher if they deem it safe and effective for you. Good luck. ;)

Are you sure that's the same unit of measurement as in the OP? That's drastically higher than cis female range even at peaks.

pg/ml vs pmol/L

http://en.wikipedia.org/wiki/Estradiol#Ranges
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KayXo

#10
July 15, 2014, 06:03:50 PM
These are indeed my levels. Pregnant ciswomen experience levels anywhere from 800-75,000 pg/ml. Some women are pregnant several times during their lives. These levels that I mention come from actual studies measuring blood levels during pregnancy.
I am not a medical doctor, nor a scientist - opinions expressed by me on the subject of HRT are merely based on my own review of some of the scientific literature over the last decade or so, on anecdotal evidence from women in various discussion forums that I have come across, and my personal experience

On HRT since early 2004
Post-op since late 2005
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Thylacin

#11
July 15, 2014, 06:44:28 PM
Quote from: KayXo on July 15, 2014, 06:03:50 PM
These are indeed my levels. Pregnant ciswomen experience levels anywhere from 800-75,000 pg/ml. Some women are pregnant several times during their lives. These levels that I mention come from actual studies measuring blood levels during pregnancy.

Wow. That's really high. O.o
Mine are around 65 pg/ml from sublingual pills.
Does that much estradiol help? Or does it just not matter after a certain point??
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HeatherR

#12
July 15, 2014, 07:03:41 PM
I don't think the goal should be cis levels but pubescent levels... Right now I'm menopausal levels lol!  And I'm swallowing, because I tried sublingual and really didn't have any positive effect, as the molecules are too large to pass through the membrane, I would go sublingual with micronized estradiol if I had a prescription for it instead
The obstacles of your past can become the gateways that lead to new beginnings.  ~Ralph Blum~
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KayXo

#13
July 15, 2014, 07:22:46 PM
Quote from: Thylacin on July 15, 2014, 06:44:28 PMDoes that much estradiol help? Or does it just not matter after a certain point??

In my case, it helped and did make a SIGNIFICANT difference. :) To each their own. 
I am not a medical doctor, nor a scientist - opinions expressed by me on the subject of HRT are merely based on my own review of some of the scientific literature over the last decade or so, on anecdotal evidence from women in various discussion forums that I have come across, and my personal experience

On HRT since early 2004
Post-op since late 2005
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KayXo

#14
July 15, 2014, 07:23:59 PM
Quote from: HeatherR on July 15, 2014, 07:03:41 PM
I don't think the goal should be cis levels but pubescent levels... Right now I'm menopausal levels lol!  And I'm swallowing, because I tried sublingual and really didn't have any positive effect, as the molecules are too large to pass through the membrane, I would go sublingual with micronized estradiol if I had a prescription for it instead

Isn't all estradiol micronized these days??
I am not a medical doctor, nor a scientist - opinions expressed by me on the subject of HRT are merely based on my own review of some of the scientific literature over the last decade or so, on anecdotal evidence from women in various discussion forums that I have come across, and my personal experience

On HRT since early 2004
Post-op since late 2005
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HeatherR

#15
July 15, 2014, 07:39:27 PM
Not according to my doctor
The obstacles of your past can become the gateways that lead to new beginnings.  ~Ralph Blum~
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HeatherR

#16
July 15, 2014, 07:39:40 PM
Well, former doctor lol
The obstacles of your past can become the gateways that lead to new beginnings.  ~Ralph Blum~
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KayXo

#17
July 15, 2014, 07:51:56 PM
I'd be surprised if all estradiol wasn't micronized these days because then, I think absorption through the digestive tract would be VERY low and ineffective. 
I am not a medical doctor, nor a scientist - opinions expressed by me on the subject of HRT are merely based on my own review of some of the scientific literature over the last decade or so, on anecdotal evidence from women in various discussion forums that I have come across, and my personal experience

On HRT since early 2004
Post-op since late 2005
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HeatherR

#18
July 15, 2014, 08:54:21 PM
Hmm, don't know!  All I know is  I want a detour around my super liver:/
The obstacles of your past can become the gateways that lead to new beginnings.  ~Ralph Blum~
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Donna Elvira

#19
July 15, 2014, 11:45:33 PM
Hi,
On my most recent lab results my E was at 310pg/ml and free T at 0,4pg/ml.

I'll be doing my GRS in a few weeks and both because of that and because of my very low T (even lower than normal for a GG) I stopped taken Spiro (already very low dose) and reduced my E intake by a third as the first step in stopping altogether a couple of weeks before surgery.

Interestingly, and to my very big surprise, since doing this about a month ago, I've had a significant spurt of breast growth.

I don't know what conclusion to draw except that, withing reason,  maybe less can be more?


Anyway, wishing you the best of luck
Donna
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