So I've heard that HRT and alcohol don't mix, but what are the actual risks, and how high are they? Should drinking be strictly prohibited? My gf does not drink much often, if ever. Maybe a beer once a month? or a mixed drink, with very little booze in it, just for taste, but should she not be doing any of this? She is on oral estrogen tabs, spiro, and progesterone. She has never drunken to any point past very early tipsiness, except tonight. Her first drunken experience. It's amusing, but I am just wondering if after this she should never do it again? Any input appreciated ^_^