Yeah, I had the dry lips and the inside of my nose was hell for a few months, but it's not too bad if your diligent with chap stick and moisturizer. I used it during the winter, the worst time of year to use it, and I was able to get through with ease. Apparently a lot of the side effects are only listed because of old claims and legal obligations. It isn't the best stuff for you, but they test your blood every month while your on it to make sure your doing OK on the inside. I had no side effects aside from the lips and dry skin, which means it's working. If you have acne on your chest or back, areas that are tough to conquer, then Accutane is an option. But it totally should be the last resort. It does work full on though. I'd first go with tazorac or retin a, both contain retinols and even fight/reverse signs of aging by improving collagen turnover...