I can completely understand where you're coming from. My friendship with one of my best friends was put under a lot of strain four years ago by her boyfriend getting super jealous of us spending time together, and it made things really awkward between us for three or four months (especially when we found out that lots of our mutual friends assumed she was cheating on him with me too... *rolls eyes*). I came out as trans not long after that, and she broke up with him maybe six months after I came out, so eventually we were able to repair our friendship, and now we're closer than ever. ^^ But it was pretty stressful at the time for both of us.
Actually, like suzifrommd above, this was one of the major motivations in my transition. That feeling of being perceived on some level as a "threat" when I was friendly with women, whether by significant others or by women themselves, was one of the most dysphoria-inducing things for me about being physically male. Pretty much all of my friends growing up had been female, and I was basically just treated as one of the girls. And it had been so much fun that all that I really wanted was for that to continue. Post puberty, though, I found my motives in wanting to be friends with women were frequently questioned (because heaven forbid a male bodied person should be genuinely interested in befriending women, right?), and it upset me so much that I actually actively avoided making female friends for many years. So being able to freely enjoy having female friends as a woman myself has been unquestionably the part of transition that has made me happiest. 🙂
