I'm surprised this hasn't been mentioned yet: Life in Aggro. It's a video game web comic. I love the art style, and they do a bunch of Final Fantasy XIV comics, which is how I got into it (back when I was playing FFXIV). They also reference a bunch of other Japanese games.
One of the comic's creators (and characters) transitioned last year (MTF), which is one of the things that helped me find the courage to admit the truth to myself. While it's still a video game comic, they occasionally have trans issues come up (more so earlier on after Cecelia's announcement).
The link goes directly to the coming out comic:
http://www.lifeinaggro.com/comic/2016/11/27The one after that with the Q&A was pretty amusing.