FYI: I'm IS.
I was born with Albinism (yup, I'm an Albino), and the strangest thing for me, is my Albinism is correcting it's self. My body is producing pigmentation. And I have blond hair now, not white. Also my eyes are correcting themselves too. I mean, I'm still legally blind, but they are working a tad better.
Also my bones are changing. My skull, shin bones, and hips are changing, and I'm 35!
When I started twenty months ago, I did a ton of research, before I started self medicating (Please do not do this, as this can be harmful, seek out a doctor before starting hrt), and don't worry, I'm up to six doctors now! These are really the only changes I've had noticed.