Taking the estradiol sublingualy allows the medication to enter the body without dealing with the stomach and digestive track. It allows more of it to effect you.
On a personal note I rarely have anything to add to this conversation, I have a nearly supernatural power to see the worse in life and myself, something I am trying to work on. For a while I have been trying in vain to find a coat that fits and I need to see a dentist too, and for the last week or so I have had a sore throat that turned into a full cold. I consider my voice my weakest link and adding the hacking cough and sore throat kills what little I can do making it even worse. Dressed in sweat pants and hoody, no make-up, no cute cloths, no breast forms, it makes feeling like myself tough.
All that said I was laying in my bed on my stomach (a position that has gotten a bit sensitive sense I started hormones, if you know what i mean) so I am watching tv and I look down and notice rather clearly that the hormones are doing there thing, nothing major and I really hope it keeps going but things have definitely changed. I mean I am still sure that given how fat I am no one would think anything of it, but still it's something and it puts a smile on my face. I even took pictures and may be a bit obsessed with them. :-P so I guess taking picture of my tater tots is what made me happy today despite everything else that's getting me down.
Serena