Define what you consider "successful" or consider a "decent" job...
I work as a poker dealer, I make about $25/hour, and no, I didn't have this job before transitioning. I got fired from two jobs in a row due to transitioning, had to apply for this job as a newly-transitioned trans woman with NO work history under my legal name, all of my references having been pre-transition, and I still got hired, and am doing quite well. And if I can do that in a field which is completely customer-service oriented, where my entire job is interacting with hundreds of people on a daily basis and making sure they're having a good time, which you'd assume is the last job a trans woman living in a conservative blue-collar city would get hired for, trust me, other people can too.
One of my best trans friends (who used to post here but doesn't anymore,) just had a job offer from a programming company for $100K/year, and in fact I have probably 5+ trans friends who are working in tech and thriving.
If you mean like being a millionaire CEO, there's not many of them. But if you mean a good stable full-time job that can pay your bills, let you live comfortably, and support a family, then yes, it's more than achievable for a vast majority of trans people.
Being trans has been proven to be a factor for hiring discrimination, but really it's not the big death sentence those in bad positions are afraid it is. Really it's just a matter of having the job skills and the people skills to be a desirable candidate, just the same as it is for cis people.