I got euphoria the next day after starting patches. I though it might just be stress relief at the time, but I've had it again each time I get a new implant, starting a few days afterward. I'm really looking forward to it again. Its such a pity it doesn't last longer.
I lost my ability to get truly angry. I'm not sure when, but it I don't think it was too long. Its easier to cry now, but I still don't do it very often. That's definitely hormone related as I notice it more strongly when my hormones change a lot.
There's some more subtle effects, but its hard to say what they are or how long. I feel totally lacking in depression right now, and that's so wonderful. It just bought tears to my eyes writing that.
I don't feel any more vulnerable, but I'm still presenting male and perhaps that helps. It makes me feel more male is the main problem.